Development and validation of a high throughput system for discovery of antigens for autoantibody detection.
An assay employing a panel of tumor-associated antigens has been validated and is available commercially (EarlyCDT®-Lung) to aid the early detection of lung cancer by measurement of serum autoantibodies. The high throughput (HTP) strategy described herein was pursued to identify new antigens to add...
Saved in:
Main Authors: | Isabel K Macdonald, Jared Allen, Andrea Murray, Celine B Parsy-Kowalska, Graham F Healey, Caroline J Chapman, Herbert F Sewell, John F R Robertson |
---|---|
Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2012
|
Subjects: | |
Online Access: | https://doaj.org/article/30b6bdc9b68c4fcf9e3b714380df206a |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Application of a high throughput method of biomarker discovery to improvement of the EarlyCDT(®)-Lung Test.
by: Isabel K Macdonald, et al.
Published: (2012) -
A droplet microfluidic platform for high-throughput photochemical reaction discovery
by: Alexandra C. Sun, et al.
Published: (2020) -
AUTOANTIBODIES TO CIRTULLINATED ANTIGENS FOR DIAGNOSIS AND PREDICTION OF CLINICAL COURSE IN EARLY RHEUMATOID ARTHRITIS
by: I. B. Belyaeva, et al.
Published: (2014) -
DRUG-seq for miniaturized high-throughput transcriptome profiling in drug discovery
by: Chaoyang Ye, et al.
Published: (2018) -
Antigen Discovery, Bioinformatics and Biological Characterization of Novel Immunodominant Babesia microti Antigens
by: Nitin Verma, et al.
Published: (2020)