Development and validation of a high throughput system for discovery of antigens for autoantibody detection.

An assay employing a panel of tumor-associated antigens has been validated and is available commercially (EarlyCDT®-Lung) to aid the early detection of lung cancer by measurement of serum autoantibodies. The high throughput (HTP) strategy described herein was pursued to identify new antigens to add...

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Auteurs principaux: Isabel K Macdonald, Jared Allen, Andrea Murray, Celine B Parsy-Kowalska, Graham F Healey, Caroline J Chapman, Herbert F Sewell, John F R Robertson
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2012
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R
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Accès en ligne:https://doaj.org/article/30b6bdc9b68c4fcf9e3b714380df206a
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