TM4SF5-dependent crosstalk between hepatocytes and macrophages to reprogram the inflammatory environment

Summary: Chronic injury to hepatocytes results in inflammation, steatohepatitis, fibrosis, and nonalcoholic fatty liver disease (NAFLD). The tetraspanin TM4SF5 is implicated in fibrosis and cancer. We investigate the role of TM4SF5 in communication between hepatocytes and macrophages (MΦs) and its p...

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Auteurs principaux: Eunmi Kim, Hyejin Um, Jinsoo Park, Jae Woo Jung, Ji Eon Kim, Haesong Lee, Eun-Ae Shin, Yangie Pinanga, Hyejin Lee, Seo Hee Nam, Jung Weon Lee
Format: article
Langue:EN
Publié: Elsevier 2021
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Accès en ligne:https://doaj.org/article/30bc3a81cc954bfe861f776a7c275d30
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