Decreased expression of miR-21, miR-26a, miR-29a, and miR-142-3p in CD4⁺ T cells and peripheral blood from tuberculosis patients.

Decreased expression of miR-21, miR-26a, miR-29a, and miR-142-3p in CD4⁺ T cells and peripheral blood from tuberculosis patients.

The vast majority of Mycobacterium tuberculosis (M. tuberculosis) infected individuals are protected from developing tuberculosis and T cells are centrally involved in this process. MicroRNAs (miRNA) regulate T-cell functions and are biomarker candidates of disease susceptibility and treatment effic...

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Main Authors: Katja Kleinsteuber, Kerrin Heesch, Stefanie Schattling, Malte Kohns, Claudia Sander-Jülch, Gerhard Walzl, Anneke Hesseling, Ertan Mayatepek, Bernhard Fleischer, Florian M Marx, Marc Jacobsen
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2013
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/30c598a8d6ad44b1ae93dc6e228df4b9
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