Tracking HIV-1 recombination to resolve its contribution to HIV-1 evolution in natural infection
Recombination contributes to HIV evolution in patients, but its identification can be difficult. Here, the authors develop a computational tool called RAPR to track recombination in patients, identify recombination hot spots, and show contribution of recombination to antibody escape.
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Nature Portfolio
2018
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oai:doaj.org-article:30d8c57d3c3f40a3b0cc066eb2a1b2842021-12-02T15:34:24ZTracking HIV-1 recombination to resolve its contribution to HIV-1 evolution in natural infection10.1038/s41467-018-04217-52041-1723https://doaj.org/article/30d8c57d3c3f40a3b0cc066eb2a1b2842018-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-04217-5https://doaj.org/toc/2041-1723Recombination contributes to HIV evolution in patients, but its identification can be difficult. Here, the authors develop a computational tool called RAPR to track recombination in patients, identify recombination hot spots, and show contribution of recombination to antibody escape.Hongshuo SongElena E. GiorgiVitaly V. GanusovFangping CaiGayathri AthreyaHyejin YoonOana CarjaBhavna HoraPeter HraberEthan Romero-SeversonChunlai JiangXiaojun LiShuyi WangHui LiJesus F. Salazar-GonzalezMaria G. SalazarNilu GoonetillekeBrandon F. KeeleDavid C. MontefioriMyron S. CohenGeorge M. ShawBeatrice H. HahnAndrew J. McMichaelBarton F. HaynesBette KorberTanmoy BhattacharyaFeng GaoNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-15 (2018) |
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DOAJ |
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DOAJ |
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EN |
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Science Q |
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Science Q Hongshuo Song Elena E. Giorgi Vitaly V. Ganusov Fangping Cai Gayathri Athreya Hyejin Yoon Oana Carja Bhavna Hora Peter Hraber Ethan Romero-Severson Chunlai Jiang Xiaojun Li Shuyi Wang Hui Li Jesus F. Salazar-Gonzalez Maria G. Salazar Nilu Goonetilleke Brandon F. Keele David C. Montefiori Myron S. Cohen George M. Shaw Beatrice H. Hahn Andrew J. McMichael Barton F. Haynes Bette Korber Tanmoy Bhattacharya Feng Gao Tracking HIV-1 recombination to resolve its contribution to HIV-1 evolution in natural infection |
| description |
Recombination contributes to HIV evolution in patients, but its identification can be difficult. Here, the authors develop a computational tool called RAPR to track recombination in patients, identify recombination hot spots, and show contribution of recombination to antibody escape. |
| format |
article |
| author |
Hongshuo Song Elena E. Giorgi Vitaly V. Ganusov Fangping Cai Gayathri Athreya Hyejin Yoon Oana Carja Bhavna Hora Peter Hraber Ethan Romero-Severson Chunlai Jiang Xiaojun Li Shuyi Wang Hui Li Jesus F. Salazar-Gonzalez Maria G. Salazar Nilu Goonetilleke Brandon F. Keele David C. Montefiori Myron S. Cohen George M. Shaw Beatrice H. Hahn Andrew J. McMichael Barton F. Haynes Bette Korber Tanmoy Bhattacharya Feng Gao |
| author_facet |
Hongshuo Song Elena E. Giorgi Vitaly V. Ganusov Fangping Cai Gayathri Athreya Hyejin Yoon Oana Carja Bhavna Hora Peter Hraber Ethan Romero-Severson Chunlai Jiang Xiaojun Li Shuyi Wang Hui Li Jesus F. Salazar-Gonzalez Maria G. Salazar Nilu Goonetilleke Brandon F. Keele David C. Montefiori Myron S. Cohen George M. Shaw Beatrice H. Hahn Andrew J. McMichael Barton F. Haynes Bette Korber Tanmoy Bhattacharya Feng Gao |
| author_sort |
Hongshuo Song |
| title |
Tracking HIV-1 recombination to resolve its contribution to HIV-1 evolution in natural infection |
| title_short |
Tracking HIV-1 recombination to resolve its contribution to HIV-1 evolution in natural infection |
| title_full |
Tracking HIV-1 recombination to resolve its contribution to HIV-1 evolution in natural infection |
| title_fullStr |
Tracking HIV-1 recombination to resolve its contribution to HIV-1 evolution in natural infection |
| title_full_unstemmed |
Tracking HIV-1 recombination to resolve its contribution to HIV-1 evolution in natural infection |
| title_sort |
tracking hiv-1 recombination to resolve its contribution to hiv-1 evolution in natural infection |
| publisher |
Nature Portfolio |
| publishDate |
2018 |
| url |
https://doaj.org/article/30d8c57d3c3f40a3b0cc066eb2a1b284 |
| work_keys_str_mv |
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