miR-1199-5p and Zeb1 function in a double-negative feedback loop potentially coordinating EMT and tumour metastasis

miRNAs have been involved in tumour development and progression. Here the authors uncover a double feedback loop between miR-1199-5p and the Zeb1, potentially coordinating a protein involved in epithelial mesenchymal transition and tumour metastasis.

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Autores principales:	Maren Diepenbruck, Stefanie Tiede, Meera Saxena, Robert Ivanek, Ravi Kiran Reddy Kalathur, Fabiana Lüönd, Nathalie Meyer-Schaller, Gerhard Christofori
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/30db2a3701054bcb82fae40e87e50062
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spelling	oai:doaj.org-article:30db2a3701054bcb82fae40e87e500622021-12-02T14:42:38ZmiR-1199-5p and Zeb1 function in a double-negative feedback loop potentially coordinating EMT and tumour metastasis10.1038/s41467-017-01197-w2041-1723https://doaj.org/article/30db2a3701054bcb82fae40e87e500622017-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01197-whttps://doaj.org/toc/2041-1723miRNAs have been involved in tumour development and progression. Here the authors uncover a double feedback loop between miR-1199-5p and the Zeb1, potentially coordinating a protein involved in epithelial mesenchymal transition and tumour metastasis.Maren DiepenbruckStefanie TiedeMeera SaxenaRobert IvanekRavi Kiran Reddy KalathurFabiana LüöndNathalie Meyer-SchallerGerhard ChristoforiNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Maren Diepenbruck Stefanie Tiede Meera Saxena Robert Ivanek Ravi Kiran Reddy Kalathur Fabiana Lüönd Nathalie Meyer-Schaller Gerhard Christofori miR-1199-5p and Zeb1 function in a double-negative feedback loop potentially coordinating EMT and tumour metastasis
description	miRNAs have been involved in tumour development and progression. Here the authors uncover a double feedback loop between miR-1199-5p and the Zeb1, potentially coordinating a protein involved in epithelial mesenchymal transition and tumour metastasis.
format	article
author	Maren Diepenbruck Stefanie Tiede Meera Saxena Robert Ivanek Ravi Kiran Reddy Kalathur Fabiana Lüönd Nathalie Meyer-Schaller Gerhard Christofori
author_facet	Maren Diepenbruck Stefanie Tiede Meera Saxena Robert Ivanek Ravi Kiran Reddy Kalathur Fabiana Lüönd Nathalie Meyer-Schaller Gerhard Christofori
author_sort	Maren Diepenbruck
title	miR-1199-5p and Zeb1 function in a double-negative feedback loop potentially coordinating EMT and tumour metastasis
title_short	miR-1199-5p and Zeb1 function in a double-negative feedback loop potentially coordinating EMT and tumour metastasis
title_full	miR-1199-5p and Zeb1 function in a double-negative feedback loop potentially coordinating EMT and tumour metastasis
title_fullStr	miR-1199-5p and Zeb1 function in a double-negative feedback loop potentially coordinating EMT and tumour metastasis
title_full_unstemmed	miR-1199-5p and Zeb1 function in a double-negative feedback loop potentially coordinating EMT and tumour metastasis
title_sort	mir-1199-5p and zeb1 function in a double-negative feedback loop potentially coordinating emt and tumour metastasis
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/30db2a3701054bcb82fae40e87e50062
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miR-1199-5p and Zeb1 function in a double-negative feedback loop potentially coordinating EMT and tumour metastasis

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