Detailed evaluation of the upper airway in the Dp(16)1Yey mouse model of Down syndrome
Abstract A high prevalence of obstructive sleep apnea (OSA) has been reported in Down syndrome (DS) owing to the coexistence of multiple predisposing factors related to its genetic abnormality, posing a challenge for the management of OSA. We hypothesized that DS mice recapitulate craniofacial abnor...
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Main Authors: | Tatsunori Takahashi, Noriaki Sakai, Tomonori Iwasaki, Timothy C. Doyle, William C. Mobley, Seiji Nishino |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2020
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Online Access: | https://doaj.org/article/30dc0ed05f7f43e0baf31e10c88765f7 |
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