Detailed evaluation of the upper airway in the Dp(16)1Yey mouse model of Down syndrome

Abstract A high prevalence of obstructive sleep apnea (OSA) has been reported in Down syndrome (DS) owing to the coexistence of multiple predisposing factors related to its genetic abnormality, posing a challenge for the management of OSA. We hypothesized that DS mice recapitulate craniofacial abnor...

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Bibliographic Details
Main Authors: Tatsunori Takahashi, Noriaki Sakai, Tomonori Iwasaki, Timothy C. Doyle, William C. Mobley, Seiji Nishino
Format: article
Language:EN
Published: Nature Portfolio 2020
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Online Access:https://doaj.org/article/30dc0ed05f7f43e0baf31e10c88765f7
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