Antibiotic-Induced Alterations of the Gut Microbiota Alter Secondary Bile Acid Production and Allow for <named-content content-type="genus-species">Clostridium difficile</named-content> Spore Germination and Outgrowth in the Large Intestine

ABSTRACT It is hypothesized that the depletion of microbial members responsible for converting primary bile acids into secondary bile acids reduces resistance to Clostridium difficile colonization. To date, inhibition of C. difficile growth by secondary bile acids has only been shown in vitro. Using...

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Bibliographic Details
Main Authors: Casey M. Theriot, Alison A. Bowman, Vincent B. Young
Format: article
Language:EN
Published: American Society for Microbiology 2016
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Online Access:https://doaj.org/article/30de0a9c763a4e8da922c0ea57b7645e
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