An in vitro model maintaining taxon-specific functional activities of the gut microbiome
The authors present an in vitro gut microbiome model that maintains the functional and compositional profiles of individual gut microbiomes, as assessed by metaproteomics. Gut microbiome responses to metformin in this model correlate with those shown in mice fed a high-fat diet.
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Nature Portfolio
2019
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oai:doaj.org-article:30e0f74146bf4947ab32a45fffacc8d82021-12-02T16:57:08ZAn in vitro model maintaining taxon-specific functional activities of the gut microbiome10.1038/s41467-019-12087-82041-1723https://doaj.org/article/30e0f74146bf4947ab32a45fffacc8d82019-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12087-8https://doaj.org/toc/2041-1723The authors present an in vitro gut microbiome model that maintains the functional and compositional profiles of individual gut microbiomes, as assessed by metaproteomics. Gut microbiome responses to metformin in this model correlate with those shown in mice fed a high-fat diet.Leyuan LiElias Abou-SamraZhibin NingXu ZhangJanice MayneJanet WangKai ChengKrystal WalkerAlain StintziDaniel FigeysNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-11 (2019) |
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Science Q Leyuan Li Elias Abou-Samra Zhibin Ning Xu Zhang Janice Mayne Janet Wang Kai Cheng Krystal Walker Alain Stintzi Daniel Figeys An in vitro model maintaining taxon-specific functional activities of the gut microbiome |
description |
The authors present an in vitro gut microbiome model that maintains the functional and compositional profiles of individual gut microbiomes, as assessed by metaproteomics. Gut microbiome responses to metformin in this model correlate with those shown in mice fed a high-fat diet. |
format |
article |
author |
Leyuan Li Elias Abou-Samra Zhibin Ning Xu Zhang Janice Mayne Janet Wang Kai Cheng Krystal Walker Alain Stintzi Daniel Figeys |
author_facet |
Leyuan Li Elias Abou-Samra Zhibin Ning Xu Zhang Janice Mayne Janet Wang Kai Cheng Krystal Walker Alain Stintzi Daniel Figeys |
author_sort |
Leyuan Li |
title |
An in vitro model maintaining taxon-specific functional activities of the gut microbiome |
title_short |
An in vitro model maintaining taxon-specific functional activities of the gut microbiome |
title_full |
An in vitro model maintaining taxon-specific functional activities of the gut microbiome |
title_fullStr |
An in vitro model maintaining taxon-specific functional activities of the gut microbiome |
title_full_unstemmed |
An in vitro model maintaining taxon-specific functional activities of the gut microbiome |
title_sort |
in vitro model maintaining taxon-specific functional activities of the gut microbiome |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/30e0f74146bf4947ab32a45fffacc8d8 |
work_keys_str_mv |
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