An in vitro model maintaining taxon-specific functional activities of the gut microbiome

The authors present an in vitro gut microbiome model that maintains the functional and compositional profiles of individual gut microbiomes, as assessed by metaproteomics. Gut microbiome responses to metformin in this model correlate with those shown in mice fed a high-fat diet.

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Autores principales: Leyuan Li, Elias Abou-Samra, Zhibin Ning, Xu Zhang, Janice Mayne, Janet Wang, Kai Cheng, Krystal Walker, Alain Stintzi, Daniel Figeys
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/30e0f74146bf4947ab32a45fffacc8d8
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spelling oai:doaj.org-article:30e0f74146bf4947ab32a45fffacc8d82021-12-02T16:57:08ZAn in vitro model maintaining taxon-specific functional activities of the gut microbiome10.1038/s41467-019-12087-82041-1723https://doaj.org/article/30e0f74146bf4947ab32a45fffacc8d82019-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12087-8https://doaj.org/toc/2041-1723The authors present an in vitro gut microbiome model that maintains the functional and compositional profiles of individual gut microbiomes, as assessed by metaproteomics. Gut microbiome responses to metformin in this model correlate with those shown in mice fed a high-fat diet.Leyuan LiElias Abou-SamraZhibin NingXu ZhangJanice MayneJanet WangKai ChengKrystal WalkerAlain StintziDaniel FigeysNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Leyuan Li
Elias Abou-Samra
Zhibin Ning
Xu Zhang
Janice Mayne
Janet Wang
Kai Cheng
Krystal Walker
Alain Stintzi
Daniel Figeys
An in vitro model maintaining taxon-specific functional activities of the gut microbiome
description The authors present an in vitro gut microbiome model that maintains the functional and compositional profiles of individual gut microbiomes, as assessed by metaproteomics. Gut microbiome responses to metformin in this model correlate with those shown in mice fed a high-fat diet.
format article
author Leyuan Li
Elias Abou-Samra
Zhibin Ning
Xu Zhang
Janice Mayne
Janet Wang
Kai Cheng
Krystal Walker
Alain Stintzi
Daniel Figeys
author_facet Leyuan Li
Elias Abou-Samra
Zhibin Ning
Xu Zhang
Janice Mayne
Janet Wang
Kai Cheng
Krystal Walker
Alain Stintzi
Daniel Figeys
author_sort Leyuan Li
title An in vitro model maintaining taxon-specific functional activities of the gut microbiome
title_short An in vitro model maintaining taxon-specific functional activities of the gut microbiome
title_full An in vitro model maintaining taxon-specific functional activities of the gut microbiome
title_fullStr An in vitro model maintaining taxon-specific functional activities of the gut microbiome
title_full_unstemmed An in vitro model maintaining taxon-specific functional activities of the gut microbiome
title_sort in vitro model maintaining taxon-specific functional activities of the gut microbiome
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/30e0f74146bf4947ab32a45fffacc8d8
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