Rifampin- or Capreomycin-Induced Remodeling of the <italic toggle="yes">Mycobacterium smegmatis</italic> Mycolic Acid Layer Is Mitigated in Synergistic Combinations with Cationic Antimicrobial Peptides

Rifampin- or Capreomycin-Induced Remodeling of the <italic toggle="yes">Mycobacterium smegmatis</italic> Mycolic Acid Layer Is Mitigated in Synergistic Combinations with Cationic Antimicrobial Peptides

ABSTRACT The mycobacterial cell wall affords natural resistance to antibiotics. Antimicrobial peptides (AMPs) modify the surface properties of mycobacteria and can act synergistically with antibiotics from differing classes. Here, we investigate the response of Mycobacterium smegmatis to the presenc...

Full description

Saved in:
Bibliographic Details
Main Authors: DeDe Kwun-Wai Man, Tokuwa Kanno, Giorgia Manzo, Brian D. Robertson, Jenny K. W. Lam, A. James Mason
Format: article
Language:EN
Published: American Society for Microbiology 2018
Subjects:
mycobacteria
NMR metabolomics
capreomycin
rifampin
synergy
tyloxapol
Microbiology
QR1-502
Online Access:https://doaj.org/article/30e2623b09474f2a90ca386387fab3dd
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doaj.org/article/30e2623b09474f2a90ca386387fab3dd

Similar Items