Epigenetic Suppression of Interferon Lambda Receptor Expression Leads to Enhanced Human Norovirus Replication <italic toggle="yes">In Vitro</italic>

ABSTRACT Human norovirus (HuNoV) is the main cause of gastroenteritis worldwide, yet no therapeutics are currently available. Here, we utilize a human norovirus replicon in human gastric tumor (HGT) cells to identify host factors involved in promoting or inhibiting HuNoV replication. We observed tha...

Full description

Saved in:
Bibliographic Details
Main Authors: Sabastine E. Arthur, Frédéric Sorgeloos, Myra Hosmillo, Ian G. Goodfellow
Format: article
Language:EN
Published: American Society for Microbiology 2019
Subjects:
Online Access:https://doaj.org/article/30e4448b669c48de83abfa27f01d9531
Tags: Add Tag
No Tags, Be the first to tag this record!