Multimodal synergisms in host stimuli drive landing response in malaria mosquitoes

Abstract Anopheles mosquitoes transmit malaria, which affects one-fifth of the world population. A comprehensive understanding of mosquito behaviour is essential for the development of novel tools for vector control and surveillance. Despite abundant research on mosquito behaviour, little is known o...

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Autores principales:	Manuela Carnaghi, Steven R. Belmain, Richard J. Hopkins, Frances M. Hawkes
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/30edb1f5c5584e1a895c5dbea57d86d8
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id	oai:doaj.org-article:30edb1f5c5584e1a895c5dbea57d86d8
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spelling	oai:doaj.org-article:30edb1f5c5584e1a895c5dbea57d86d82021-12-02T13:26:42ZMultimodal synergisms in host stimuli drive landing response in malaria mosquitoes10.1038/s41598-021-86772-42045-2322https://doaj.org/article/30edb1f5c5584e1a895c5dbea57d86d82021-04-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-86772-4https://doaj.org/toc/2045-2322Abstract Anopheles mosquitoes transmit malaria, which affects one-fifth of the world population. A comprehensive understanding of mosquito behaviour is essential for the development of novel tools for vector control and surveillance. Despite abundant research on mosquito behaviour, little is known on the stimuli that drive malaria vectors during the landing phase of host-seeking. Using behavioural assays with a multimodal step approach we quantified both the individual and the combined effect of three host-associated stimuli in eliciting landing in Anopheles coluzzii females. We demonstrated that visual, olfactory and thermal sensory stimuli interact synergistically to increase the landing response. Furthermore, if considering only the final outcome (i.e. landing response), our insect model can bypass the absence of either a thermal or a visual stimulus, provided that at least one of these is presented simultaneously with the olfactory stimuli, suggesting that landing is the result of a flexible but accurate stimuli integration. These results have important implications for the development of mosquito control and surveillance tools.Manuela CarnaghiSteven R. BelmainRichard J. HopkinsFrances M. HawkesNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Manuela Carnaghi Steven R. Belmain Richard J. Hopkins Frances M. Hawkes Multimodal synergisms in host stimuli drive landing response in malaria mosquitoes
description	Abstract Anopheles mosquitoes transmit malaria, which affects one-fifth of the world population. A comprehensive understanding of mosquito behaviour is essential for the development of novel tools for vector control and surveillance. Despite abundant research on mosquito behaviour, little is known on the stimuli that drive malaria vectors during the landing phase of host-seeking. Using behavioural assays with a multimodal step approach we quantified both the individual and the combined effect of three host-associated stimuli in eliciting landing in Anopheles coluzzii females. We demonstrated that visual, olfactory and thermal sensory stimuli interact synergistically to increase the landing response. Furthermore, if considering only the final outcome (i.e. landing response), our insect model can bypass the absence of either a thermal or a visual stimulus, provided that at least one of these is presented simultaneously with the olfactory stimuli, suggesting that landing is the result of a flexible but accurate stimuli integration. These results have important implications for the development of mosquito control and surveillance tools.
format	article
author	Manuela Carnaghi Steven R. Belmain Richard J. Hopkins Frances M. Hawkes
author_facet	Manuela Carnaghi Steven R. Belmain Richard J. Hopkins Frances M. Hawkes
author_sort	Manuela Carnaghi
title	Multimodal synergisms in host stimuli drive landing response in malaria mosquitoes
title_short	Multimodal synergisms in host stimuli drive landing response in malaria mosquitoes
title_full	Multimodal synergisms in host stimuli drive landing response in malaria mosquitoes
title_fullStr	Multimodal synergisms in host stimuli drive landing response in malaria mosquitoes
title_full_unstemmed	Multimodal synergisms in host stimuli drive landing response in malaria mosquitoes
title_sort	multimodal synergisms in host stimuli drive landing response in malaria mosquitoes
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/30edb1f5c5584e1a895c5dbea57d86d8
work_keys_str_mv	AT manuelacarnaghi multimodalsynergismsinhoststimulidrivelandingresponseinmalariamosquitoes AT stevenrbelmain multimodalsynergismsinhoststimulidrivelandingresponseinmalariamosquitoes AT richardjhopkins multimodalsynergismsinhoststimulidrivelandingresponseinmalariamosquitoes AT francesmhawkes multimodalsynergismsinhoststimulidrivelandingresponseinmalariamosquitoes
_version_	1718393021230219264

Multimodal synergisms in host stimuli drive landing response in malaria mosquitoes

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