IMMUNOGENICITY OF THE THIRD GENERATION HEPATITIS B VACCINE (pre-S1/pre-S2/S)

Currently, second-generation hepatitis B vaccines are widely used. They are produced in biotechnological eukaryotic yeast-based systems and contain the S-protein domain of HBsAg particle in the complete absence of pre-S1 and pre-S2 domains. At the same time, these antigens were proved to significant...

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Autores principales: E. V. Esaulenko, A. A. Sukhoruk, K. A. Zakharov, A. A. Yakovlev
Formato: article
Lenguaje:RU
Publicado: Sankt-Peterburg : NIIÈM imeni Pastera 2018
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Acceso en línea:https://doaj.org/article/30f2051813c64d6ca613589418c60945
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