A Case of Disseminated Herpes Zoster Presenting as Vesicles Limited to Skin Lesions with Lymphoma Cutis Involvement

After primary infection, varicella zoster virus (VZV) causes prolonged latent infections that may reactivate, depending on the immunologic status of the host. We present a case of VZV reactivation in a 10-year-old male patient that underwent unrelated peripheral blood stem cell transplantation (uPBS...

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Autores principales:	Joo Yup Lee, Hyun Mi Kang, Seong Koo Kim, Jae Wook Lee, Nack-Gyun Chung, Dae Chul Jeong, Bin Cho
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	immunocompromised varicella zoster virus reactivation Pediatrics RJ1-570
Acceso en línea:	https://doaj.org/article/30f9a6ffa89740d0a6020500048f7e43
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spelling	oai:doaj.org-article:30f9a6ffa89740d0a6020500048f7e432021-11-25T17:14:06ZA Case of Disseminated Herpes Zoster Presenting as Vesicles Limited to Skin Lesions with Lymphoma Cutis Involvement10.3390/children81109762227-9067https://doaj.org/article/30f9a6ffa89740d0a6020500048f7e432021-10-01T00:00:00Zhttps://www.mdpi.com/2227-9067/8/11/976https://doaj.org/toc/2227-9067After primary infection, varicella zoster virus (VZV) causes prolonged latent infections that may reactivate, depending on the immunologic status of the host. We present a case of VZV reactivation in a 10-year-old male patient that underwent unrelated peripheral blood stem cell transplantation (uPBSCT) for T-lymphoblastic lymphoma with lymphoma cutis lesions. This patient had a history of herpes zoster involving the right L2-5 dermatome and trigeminal V1 dermatome prior to uPBSCT. Three months post-uPBSCT, the patient’s underlying disease relapsed, and the patient presented with lymphoma cutis lesions. A few days after a skin biopsy was performed to pathologically confirm skin relapse, vesicles appeared only involving the skin areas with lymphoma cutis. This case illustrates how decreased areas of epidermal immune mechanisms may cause atypical presentations of varicella infection.Joo Yup LeeHyun Mi KangSeong Koo KimJae Wook LeeNack-Gyun ChungDae Chul JeongBin ChoMDPI AGarticleimmunocompromisedvaricella zoster virusreactivationPediatricsRJ1-570ENChildren, Vol 8, Iss 976, p 976 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	immunocompromised varicella zoster virus reactivation Pediatrics RJ1-570
spellingShingle	immunocompromised varicella zoster virus reactivation Pediatrics RJ1-570 Joo Yup Lee Hyun Mi Kang Seong Koo Kim Jae Wook Lee Nack-Gyun Chung Dae Chul Jeong Bin Cho A Case of Disseminated Herpes Zoster Presenting as Vesicles Limited to Skin Lesions with Lymphoma Cutis Involvement
description	After primary infection, varicella zoster virus (VZV) causes prolonged latent infections that may reactivate, depending on the immunologic status of the host. We present a case of VZV reactivation in a 10-year-old male patient that underwent unrelated peripheral blood stem cell transplantation (uPBSCT) for T-lymphoblastic lymphoma with lymphoma cutis lesions. This patient had a history of herpes zoster involving the right L2-5 dermatome and trigeminal V1 dermatome prior to uPBSCT. Three months post-uPBSCT, the patient’s underlying disease relapsed, and the patient presented with lymphoma cutis lesions. A few days after a skin biopsy was performed to pathologically confirm skin relapse, vesicles appeared only involving the skin areas with lymphoma cutis. This case illustrates how decreased areas of epidermal immune mechanisms may cause atypical presentations of varicella infection.
format	article
author	Joo Yup Lee Hyun Mi Kang Seong Koo Kim Jae Wook Lee Nack-Gyun Chung Dae Chul Jeong Bin Cho
author_facet	Joo Yup Lee Hyun Mi Kang Seong Koo Kim Jae Wook Lee Nack-Gyun Chung Dae Chul Jeong Bin Cho
author_sort	Joo Yup Lee
title	A Case of Disseminated Herpes Zoster Presenting as Vesicles Limited to Skin Lesions with Lymphoma Cutis Involvement
title_short	A Case of Disseminated Herpes Zoster Presenting as Vesicles Limited to Skin Lesions with Lymphoma Cutis Involvement
title_full	A Case of Disseminated Herpes Zoster Presenting as Vesicles Limited to Skin Lesions with Lymphoma Cutis Involvement
title_fullStr	A Case of Disseminated Herpes Zoster Presenting as Vesicles Limited to Skin Lesions with Lymphoma Cutis Involvement
title_full_unstemmed	A Case of Disseminated Herpes Zoster Presenting as Vesicles Limited to Skin Lesions with Lymphoma Cutis Involvement
title_sort	case of disseminated herpes zoster presenting as vesicles limited to skin lesions with lymphoma cutis involvement
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/30f9a6ffa89740d0a6020500048f7e43
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A Case of Disseminated Herpes Zoster Presenting as Vesicles Limited to Skin Lesions with Lymphoma Cutis Involvement

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