Stem cell and neurogenic gene-expression profiles link prostate basal cells to aggressive prostate cancer

Gene-expression profiles can be used to predict the prognosis of cancer patients. Here, the authors describe gene expression profiles of human prostate epithelial lineages and show that basal cells have intrinsic stem and neurogenic properties, and molecularly resemble aggressive prostate cancer.

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Autores principales:	Dingxiao Zhang, Daechan Park, Yi Zhong, Yue Lu, Kiera Rycaj, Shuai Gong, Xin Chen, Xin Liu, Hsueh-Ping Chao, Pamela Whitney, Tammy Calhoun-Davis, Yoko Takata, Jianjun Shen, Vishwanath R. Iyer, Dean G. Tang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/30fa2e5e53b1479e85a8f8950ff04d3a
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spelling	oai:doaj.org-article:30fa2e5e53b1479e85a8f8950ff04d3a2021-12-02T14:38:33ZStem cell and neurogenic gene-expression profiles link prostate basal cells to aggressive prostate cancer10.1038/ncomms107982041-1723https://doaj.org/article/30fa2e5e53b1479e85a8f8950ff04d3a2016-02-01T00:00:00Zhttps://doi.org/10.1038/ncomms10798https://doaj.org/toc/2041-1723Gene-expression profiles can be used to predict the prognosis of cancer patients. Here, the authors describe gene expression profiles of human prostate epithelial lineages and show that basal cells have intrinsic stem and neurogenic properties, and molecularly resemble aggressive prostate cancer.Dingxiao ZhangDaechan ParkYi ZhongYue LuKiera RycajShuai GongXin ChenXin LiuHsueh-Ping ChaoPamela WhitneyTammy Calhoun-DavisYoko TakataJianjun ShenVishwanath R. IyerDean G. TangNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Dingxiao Zhang Daechan Park Yi Zhong Yue Lu Kiera Rycaj Shuai Gong Xin Chen Xin Liu Hsueh-Ping Chao Pamela Whitney Tammy Calhoun-Davis Yoko Takata Jianjun Shen Vishwanath R. Iyer Dean G. Tang Stem cell and neurogenic gene-expression profiles link prostate basal cells to aggressive prostate cancer
description	Gene-expression profiles can be used to predict the prognosis of cancer patients. Here, the authors describe gene expression profiles of human prostate epithelial lineages and show that basal cells have intrinsic stem and neurogenic properties, and molecularly resemble aggressive prostate cancer.
format	article
author	Dingxiao Zhang Daechan Park Yi Zhong Yue Lu Kiera Rycaj Shuai Gong Xin Chen Xin Liu Hsueh-Ping Chao Pamela Whitney Tammy Calhoun-Davis Yoko Takata Jianjun Shen Vishwanath R. Iyer Dean G. Tang
author_facet	Dingxiao Zhang Daechan Park Yi Zhong Yue Lu Kiera Rycaj Shuai Gong Xin Chen Xin Liu Hsueh-Ping Chao Pamela Whitney Tammy Calhoun-Davis Yoko Takata Jianjun Shen Vishwanath R. Iyer Dean G. Tang
author_sort	Dingxiao Zhang
title	Stem cell and neurogenic gene-expression profiles link prostate basal cells to aggressive prostate cancer
title_short	Stem cell and neurogenic gene-expression profiles link prostate basal cells to aggressive prostate cancer
title_full	Stem cell and neurogenic gene-expression profiles link prostate basal cells to aggressive prostate cancer
title_fullStr	Stem cell and neurogenic gene-expression profiles link prostate basal cells to aggressive prostate cancer
title_full_unstemmed	Stem cell and neurogenic gene-expression profiles link prostate basal cells to aggressive prostate cancer
title_sort	stem cell and neurogenic gene-expression profiles link prostate basal cells to aggressive prostate cancer
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/30fa2e5e53b1479e85a8f8950ff04d3a
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Stem cell and neurogenic gene-expression profiles link prostate basal cells to aggressive prostate cancer

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