Investigation on the Correlation between Serum Immune Factor Levels and Allergic Constitution in Children with Infectious Mononucleosis

Objective. To investigate the correlation between serum immune factor levels and allergic constitution in children with infectious mononucleosis. Methods. A total of 120 children who visited our hospital from March, 2019, to December, 2020, were selected as the research objects, and 40 children who...

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Autores principales:	Hong Sun, Weiqun Wang, Chenglei Lin, Min Chen
Formato:	article
Lenguaje:	EN
Publicado:	Hindawi Limited 2021
Materias:	Other systems of medicine RZ201-999
Acceso en línea:	https://doaj.org/article/3119d029f45f4f7aa54aabec8f1506c6
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spelling	oai:doaj.org-article:3119d029f45f4f7aa54aabec8f1506c62021-11-08T02:36:31ZInvestigation on the Correlation between Serum Immune Factor Levels and Allergic Constitution in Children with Infectious Mononucleosis1741-428810.1155/2021/7368642https://doaj.org/article/3119d029f45f4f7aa54aabec8f1506c62021-01-01T00:00:00Zhttp://dx.doi.org/10.1155/2021/7368642https://doaj.org/toc/1741-4288Objective. To investigate the correlation between serum immune factor levels and allergic constitution in children with infectious mononucleosis. Methods. A total of 120 children who visited our hospital from March, 2019, to December, 2020, were selected as the research objects, and 40 children who came to our hospital for physical examination were included in the control group (CG). 40 children with IM were classified into the IM group (IG), and 40 IM children with allergic rhinitis, allergic dermatitis, asthma, and other allergic diseases were classified into the IM allergy group (AG). On the second day of admission, 5 ml of fasting venous blood was collected from all children in the early morning to observe the serum IgE level, the level of lymphocyte subsets, and the level of immunoglobulin of the patient. Results. The serum CD3, CD4, and CD8 levels of children in AG were significantly higher than those in IG and CG (P<0.05). The serum IgE, IgA, IgM, and IgG levels of children in AG were significantly higher than those of IG and CG (P<0.05). The serum IgE levels of children in AG were positively correlated with the serum CD3, CD4, and CD8 levels (P<0.05). There was a positive correlation between the serum IgE level and serum IgA, IgM, and IgG levels in children with AG (P<0.05). Conclusion. The results of this study showed that there may be a certain relationship between allergic constitution and the incidence, clinical manifestations, and prognosis of infectious mononucleosis. IgE level can be used as a reference index for the early severity of IM clinical symptoms.Hong SunWeiqun WangChenglei LinMin ChenHindawi LimitedarticleOther systems of medicineRZ201-999ENEvidence-Based Complementary and Alternative Medicine, Vol 2021 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Other systems of medicine RZ201-999
spellingShingle	Other systems of medicine RZ201-999 Hong Sun Weiqun Wang Chenglei Lin Min Chen Investigation on the Correlation between Serum Immune Factor Levels and Allergic Constitution in Children with Infectious Mononucleosis
description	Objective. To investigate the correlation between serum immune factor levels and allergic constitution in children with infectious mononucleosis. Methods. A total of 120 children who visited our hospital from March, 2019, to December, 2020, were selected as the research objects, and 40 children who came to our hospital for physical examination were included in the control group (CG). 40 children with IM were classified into the IM group (IG), and 40 IM children with allergic rhinitis, allergic dermatitis, asthma, and other allergic diseases were classified into the IM allergy group (AG). On the second day of admission, 5 ml of fasting venous blood was collected from all children in the early morning to observe the serum IgE level, the level of lymphocyte subsets, and the level of immunoglobulin of the patient. Results. The serum CD3, CD4, and CD8 levels of children in AG were significantly higher than those in IG and CG (P<0.05). The serum IgE, IgA, IgM, and IgG levels of children in AG were significantly higher than those of IG and CG (P<0.05). The serum IgE levels of children in AG were positively correlated with the serum CD3, CD4, and CD8 levels (P<0.05). There was a positive correlation between the serum IgE level and serum IgA, IgM, and IgG levels in children with AG (P<0.05). Conclusion. The results of this study showed that there may be a certain relationship between allergic constitution and the incidence, clinical manifestations, and prognosis of infectious mononucleosis. IgE level can be used as a reference index for the early severity of IM clinical symptoms.
format	article
author	Hong Sun Weiqun Wang Chenglei Lin Min Chen
author_facet	Hong Sun Weiqun Wang Chenglei Lin Min Chen
author_sort	Hong Sun
title	Investigation on the Correlation between Serum Immune Factor Levels and Allergic Constitution in Children with Infectious Mononucleosis
title_short	Investigation on the Correlation between Serum Immune Factor Levels and Allergic Constitution in Children with Infectious Mononucleosis
title_full	Investigation on the Correlation between Serum Immune Factor Levels and Allergic Constitution in Children with Infectious Mononucleosis
title_fullStr	Investigation on the Correlation between Serum Immune Factor Levels and Allergic Constitution in Children with Infectious Mononucleosis
title_full_unstemmed	Investigation on the Correlation between Serum Immune Factor Levels and Allergic Constitution in Children with Infectious Mononucleosis
title_sort	investigation on the correlation between serum immune factor levels and allergic constitution in children with infectious mononucleosis
publisher	Hindawi Limited
publishDate	2021
url	https://doaj.org/article/3119d029f45f4f7aa54aabec8f1506c6
work_keys_str_mv	AT hongsun investigationonthecorrelationbetweenserumimmunefactorlevelsandallergicconstitutioninchildrenwithinfectiousmononucleosis AT weiqunwang investigationonthecorrelationbetweenserumimmunefactorlevelsandallergicconstitutioninchildrenwithinfectiousmononucleosis AT chengleilin investigationonthecorrelationbetweenserumimmunefactorlevelsandallergicconstitutioninchildrenwithinfectiousmononucleosis AT minchen investigationonthecorrelationbetweenserumimmunefactorlevelsandallergicconstitutioninchildrenwithinfectiousmononucleosis
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Investigation on the Correlation between Serum Immune Factor Levels and Allergic Constitution in Children with Infectious Mononucleosis

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