Regulation of cardiomyocyte behavior in zebrafish trabeculation by Neuregulin 2a signaling
Cardiac trabeculae (which are sponge-like muscular structures) form mostly as a result of cardiomyocyte (CM) delamination in zebrafish. Here, the authors identify Nrg2a in zebrafish as a key regulator of trabeculation, and atrial and non-contractile CMs also respond to Nrg2a despite not forming trab...
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Nature Portfolio
2017
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oai:doaj.org-article:311ce37c5db44cac88ab4718b4dabeb32021-12-02T15:37:04ZRegulation of cardiomyocyte behavior in zebrafish trabeculation by Neuregulin 2a signaling10.1038/ncomms152812041-1723https://doaj.org/article/311ce37c5db44cac88ab4718b4dabeb32017-05-01T00:00:00Zhttps://doi.org/10.1038/ncomms15281https://doaj.org/toc/2041-1723Cardiac trabeculae (which are sponge-like muscular structures) form mostly as a result of cardiomyocyte (CM) delamination in zebrafish. Here, the authors identify Nrg2a in zebrafish as a key regulator of trabeculation, and atrial and non-contractile CMs also respond to Nrg2a despite not forming trabeculae.S. Javad RasouliDidier Y. R. StainierNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-11 (2017) |
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Science Q S. Javad Rasouli Didier Y. R. Stainier Regulation of cardiomyocyte behavior in zebrafish trabeculation by Neuregulin 2a signaling |
description |
Cardiac trabeculae (which are sponge-like muscular structures) form mostly as a result of cardiomyocyte (CM) delamination in zebrafish. Here, the authors identify Nrg2a in zebrafish as a key regulator of trabeculation, and atrial and non-contractile CMs also respond to Nrg2a despite not forming trabeculae. |
format |
article |
author |
S. Javad Rasouli Didier Y. R. Stainier |
author_facet |
S. Javad Rasouli Didier Y. R. Stainier |
author_sort |
S. Javad Rasouli |
title |
Regulation of cardiomyocyte behavior in zebrafish trabeculation by Neuregulin 2a signaling |
title_short |
Regulation of cardiomyocyte behavior in zebrafish trabeculation by Neuregulin 2a signaling |
title_full |
Regulation of cardiomyocyte behavior in zebrafish trabeculation by Neuregulin 2a signaling |
title_fullStr |
Regulation of cardiomyocyte behavior in zebrafish trabeculation by Neuregulin 2a signaling |
title_full_unstemmed |
Regulation of cardiomyocyte behavior in zebrafish trabeculation by Neuregulin 2a signaling |
title_sort |
regulation of cardiomyocyte behavior in zebrafish trabeculation by neuregulin 2a signaling |
publisher |
Nature Portfolio |
publishDate |
2017 |
url |
https://doaj.org/article/311ce37c5db44cac88ab4718b4dabeb3 |
work_keys_str_mv |
AT sjavadrasouli regulationofcardiomyocytebehaviorinzebrafishtrabeculationbyneuregulin2asignaling AT didieryrstainier regulationofcardiomyocytebehaviorinzebrafishtrabeculationbyneuregulin2asignaling |
_version_ |
1718386223076081664 |