Nonalcoholic Fatty Liver Disease and Chronic Kidney Disease: A Review of Links and Risks

Amanda Cheung, Aijaz Ahmed Division of Gastroenterology and Hepatology, Stanford University School of Medicine, Stanford, CA, USACorrespondence: Amanda CheungDivision of Gastroenterology and Hepatology, Stanford University School of Medicine, 750 Welch Road, Suite 210, Stanford, CA, 94304, USATel +1...

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Autores principales:	Cheung A, Ahmed A
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2021
Materias:	nonalcoholic fatty liver disease chronic kidney disease mortality metabolic syndrome gut-liver axis gut-kidney axis liver-kidney axis Diseases of the digestive system. Gastroenterology RC799-869
Acceso en línea:	https://doaj.org/article/312ed4424b72428eabd3dfe00ffb9f7f
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spelling	oai:doaj.org-article:312ed4424b72428eabd3dfe00ffb9f7f2021-11-18T19:40:25ZNonalcoholic Fatty Liver Disease and Chronic Kidney Disease: A Review of Links and Risks1178-7023https://doaj.org/article/312ed4424b72428eabd3dfe00ffb9f7f2021-11-01T00:00:00Zhttps://www.dovepress.com/nonalcoholic-fatty-liver-disease-and-chronic-kidney-disease-a-review-o-peer-reviewed-fulltext-article-CEGhttps://doaj.org/toc/1178-7023Amanda Cheung, Aijaz Ahmed Division of Gastroenterology and Hepatology, Stanford University School of Medicine, Stanford, CA, USACorrespondence: Amanda CheungDivision of Gastroenterology and Hepatology, Stanford University School of Medicine, 750 Welch Road, Suite 210, Stanford, CA, 94304, USATel +1 650-498-6080Fax +1 650-498-5692Email cheungac@stanford.eduAbstract: Nonalcoholic fatty liver disease and chronic kidney disease are both chronic conditions with rapidly increasing prevalence and incidence worldwide that have led to a significant burden on health-care systems. The association between these two disease entities is partly attributed to shared cardiometabolic comorbidities including diabetes, hypertension, obesity, and metabolic syndrome. However, independent of these overlapping risks, there are increased rates and more severe CKD in NAFLD patients. Conversely, more progressive NAFLD is seen with advanced stages of kidney injury. In addition to overlapping risk factors, shared pathogenic mechanisms suggest these two disease entities may resemble different manifestations of a single underlying disease process.Keywords: nonalcoholic fatty liver disease, chronic kidney disease, mortality, metabolic syndrome, gut-liver axis, gut-kidney axis, liver-kidney axisCheung AAhmed ADove Medical Pressarticlenonalcoholic fatty liver diseasechronic kidney diseasemortalitymetabolic syndromegut-liver axisgut-kidney axisliver-kidney axisDiseases of the digestive system. GastroenterologyRC799-869ENClinical and Experimental Gastroenterology, Vol Volume 14, Pp 457-465 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	nonalcoholic fatty liver disease chronic kidney disease mortality metabolic syndrome gut-liver axis gut-kidney axis liver-kidney axis Diseases of the digestive system. Gastroenterology RC799-869
spellingShingle	nonalcoholic fatty liver disease chronic kidney disease mortality metabolic syndrome gut-liver axis gut-kidney axis liver-kidney axis Diseases of the digestive system. Gastroenterology RC799-869 Cheung A Ahmed A Nonalcoholic Fatty Liver Disease and Chronic Kidney Disease: A Review of Links and Risks
description	Amanda Cheung, Aijaz Ahmed Division of Gastroenterology and Hepatology, Stanford University School of Medicine, Stanford, CA, USACorrespondence: Amanda CheungDivision of Gastroenterology and Hepatology, Stanford University School of Medicine, 750 Welch Road, Suite 210, Stanford, CA, 94304, USATel +1 650-498-6080Fax +1 650-498-5692Email cheungac@stanford.eduAbstract: Nonalcoholic fatty liver disease and chronic kidney disease are both chronic conditions with rapidly increasing prevalence and incidence worldwide that have led to a significant burden on health-care systems. The association between these two disease entities is partly attributed to shared cardiometabolic comorbidities including diabetes, hypertension, obesity, and metabolic syndrome. However, independent of these overlapping risks, there are increased rates and more severe CKD in NAFLD patients. Conversely, more progressive NAFLD is seen with advanced stages of kidney injury. In addition to overlapping risk factors, shared pathogenic mechanisms suggest these two disease entities may resemble different manifestations of a single underlying disease process.Keywords: nonalcoholic fatty liver disease, chronic kidney disease, mortality, metabolic syndrome, gut-liver axis, gut-kidney axis, liver-kidney axis
format	article
author	Cheung A Ahmed A
author_facet	Cheung A Ahmed A
author_sort	Cheung A
title	Nonalcoholic Fatty Liver Disease and Chronic Kidney Disease: A Review of Links and Risks
title_short	Nonalcoholic Fatty Liver Disease and Chronic Kidney Disease: A Review of Links and Risks
title_full	Nonalcoholic Fatty Liver Disease and Chronic Kidney Disease: A Review of Links and Risks
title_fullStr	Nonalcoholic Fatty Liver Disease and Chronic Kidney Disease: A Review of Links and Risks
title_full_unstemmed	Nonalcoholic Fatty Liver Disease and Chronic Kidney Disease: A Review of Links and Risks
title_sort	nonalcoholic fatty liver disease and chronic kidney disease: a review of links and risks
publisher	Dove Medical Press
publishDate	2021
url	https://doaj.org/article/312ed4424b72428eabd3dfe00ffb9f7f
work_keys_str_mv	AT cheunga nonalcoholicfattyliverdiseaseandchronickidneydiseaseareviewoflinksandrisks AT ahmeda nonalcoholicfattyliverdiseaseandchronickidneydiseaseareviewoflinksandrisks
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Nonalcoholic Fatty Liver Disease and Chronic Kidney Disease: A Review of Links and Risks

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