Elevated 5hmC levels characterize DNA of the cerebellum in Parkinson’s disease

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Elevated 5hmC levels characterize DNA of the cerebellum in Parkinson’s disease

Abstract 5-methylcytosine and the oxidation product 5-hydroxymethylcytosine are two prominent epigenetic variants of the cytosine base in nuclear DNA of mammalian brains. We measured levels of 5-methylcytosine and 5-hydroxymethylcytosine by enzyme-linked immunosorbent assay in DNA from post-mortem c...

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Autores principales:	Reinhard Stöger, Paula J. Scaife, Freya Shephard, Lisa Chakrabarti
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Neurology. Diseases of the nervous system RC346-429
Acceso en línea:	https://doaj.org/article/313bead6c40041298b4aafaba6c38a62
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

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