A joint analysis of influenza-associated hospitalizations and mortality in Hong Kong, 1998–2013

Abstract Influenza viruses may cause severe human infections leading to hospitalization or death. Linear regression models were fitted to population-based data on hospitalizations and deaths. Surveillance data on influenza virus activity permitted inference on influenza-associated hospitalizations a...

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Autores principales:	Peng Wu, Anne M. Presanis, Helen S. Bond, Eric H. Y. Lau, Vicky J. Fang, Benjamin J. Cowling
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/31423552dbc14d25b46c6fd9c7474011
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spelling	oai:doaj.org-article:31423552dbc14d25b46c6fd9c74740112021-12-02T11:53:01ZA joint analysis of influenza-associated hospitalizations and mortality in Hong Kong, 1998–201310.1038/s41598-017-01021-x2045-2322https://doaj.org/article/31423552dbc14d25b46c6fd9c74740112017-04-01T00:00:00Zhttps://doi.org/10.1038/s41598-017-01021-xhttps://doaj.org/toc/2045-2322Abstract Influenza viruses may cause severe human infections leading to hospitalization or death. Linear regression models were fitted to population-based data on hospitalizations and deaths. Surveillance data on influenza virus activity permitted inference on influenza-associated hospitalizations and deaths. The ratios of these estimates were used as a potential indicator of severity. Influenza was associated with 431 (95% CrI: 358–503) respiratory deaths and 12,700 (95% CrI: 11,700–13,700) respiratory hospitalizations per year. Majority of the excess deaths occurred in persons ≥65 y of age. The ratios of deaths to hospitalizations in adults ≥65 y were significantly higher for influenza A(H1N1) and A(H1N1)pdm09 compared to A(H3N2) and B. Substantial disease burden associated with influenza viruses were estimated in Hong Kong particularly among children and elderly in 1998–2013. Infections with influenza A(H1N1) was suggested to be more serious than A(H3N2) in older adults.Peng WuAnne M. PresanisHelen S. BondEric H. Y. LauVicky J. FangBenjamin J. CowlingNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 7, Iss 1, Pp 1-7 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Peng Wu Anne M. Presanis Helen S. Bond Eric H. Y. Lau Vicky J. Fang Benjamin J. Cowling A joint analysis of influenza-associated hospitalizations and mortality in Hong Kong, 1998–2013
description	Abstract Influenza viruses may cause severe human infections leading to hospitalization or death. Linear regression models were fitted to population-based data on hospitalizations and deaths. Surveillance data on influenza virus activity permitted inference on influenza-associated hospitalizations and deaths. The ratios of these estimates were used as a potential indicator of severity. Influenza was associated with 431 (95% CrI: 358–503) respiratory deaths and 12,700 (95% CrI: 11,700–13,700) respiratory hospitalizations per year. Majority of the excess deaths occurred in persons ≥65 y of age. The ratios of deaths to hospitalizations in adults ≥65 y were significantly higher for influenza A(H1N1) and A(H1N1)pdm09 compared to A(H3N2) and B. Substantial disease burden associated with influenza viruses were estimated in Hong Kong particularly among children and elderly in 1998–2013. Infections with influenza A(H1N1) was suggested to be more serious than A(H3N2) in older adults.
format	article
author	Peng Wu Anne M. Presanis Helen S. Bond Eric H. Y. Lau Vicky J. Fang Benjamin J. Cowling
author_facet	Peng Wu Anne M. Presanis Helen S. Bond Eric H. Y. Lau Vicky J. Fang Benjamin J. Cowling
author_sort	Peng Wu
title	A joint analysis of influenza-associated hospitalizations and mortality in Hong Kong, 1998–2013
title_short	A joint analysis of influenza-associated hospitalizations and mortality in Hong Kong, 1998–2013
title_full	A joint analysis of influenza-associated hospitalizations and mortality in Hong Kong, 1998–2013
title_fullStr	A joint analysis of influenza-associated hospitalizations and mortality in Hong Kong, 1998–2013
title_full_unstemmed	A joint analysis of influenza-associated hospitalizations and mortality in Hong Kong, 1998–2013
title_sort	joint analysis of influenza-associated hospitalizations and mortality in hong kong, 1998–2013
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/31423552dbc14d25b46c6fd9c7474011
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A joint analysis of influenza-associated hospitalizations and mortality in Hong Kong, 1998–2013

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