MANF regulates hypothalamic control of food intake and body weight

MANF regulates hypothalamic control of food intake and body weight

MANF is a neurotrophic factor that is secreted but also mediates the unfolded protein response acting intracellularly. Here, the authors show that MANF expression in the brain is influenced by nutritional cues, and hypothalamic MANF influences food intake and systemic energy homeostasis.

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Detalles Bibliográficos
Autores principales: Su Yang, Huiming Yang, Renbao Chang, Peng Yin, Yang Yang, Weili Yang, Shanshan Huang, Marta A. Gaertig, Shihua Li, Xiao-Jiang Li
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Science
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Acceso en línea:https://doaj.org/article/3145dea6879743cc979c30ea0084a9a5
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