Designing development programs for non-traditional antibacterial agents

Non-traditional antibacterial agents are challenging to develop. In this Perspective, the authors argue that the distinction between traditional and non-traditional agents has only limited relevance for regulatory purposes, although products with non-traditional goals focused on population-level ben...

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Autores principales: John H. Rex, Holly Fernandez Lynch, I. Glenn Cohen, Jonathan J. Darrow, Kevin Outterson
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/3146f09e95be41bd9cb39854de101287
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Sumario:Non-traditional antibacterial agents are challenging to develop. In this Perspective, the authors argue that the distinction between traditional and non-traditional agents has only limited relevance for regulatory purposes, although products with non-traditional goals focused on population-level benefits might benefit from extension of current paradigms.