Molecular decoy to the Y-box binding protein-1 suppresses the growth of breast and prostate cancer cells whilst sparing normal cell viability.
The Y-box binding protein-1 (YB-1) is an oncogenic transcription/translation factor that is activated by phosphorylation at S102 whereby it induces the expression of growth promoting genes such as EGFR and HER-2. We recently illustrated by an in vitro kinase assay that a novel peptide to YB-1 was hi...
Guardado en:
Autores principales: | Jennifer H Law, Yvonne Li, Karen To, Michelle Wang, Arezoo Astanehe, Karen Lambie, Jaspreet Dhillon, Steven J M Jones, Martin E Gleave, Connie J Eaves, Sandra E Dunn |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2010
|
Materias: | |
Acceso en línea: | https://doaj.org/article/3147afe5871e4fafa2b7c7e078bf833e |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Exosomes harbor B cell targets in pancreatic adenocarcinoma and exert decoy function against complement-mediated cytotoxicity
por: Michela Capello, et al.
Publicado: (2019) -
Immunology of fibrotic lung disease: managing infections whilst preventing autoimmunity?
por: Thomas Hügle
Publicado: (2011) -
Ageing is associated with disrupted reinforcement learning whilst learning to help others is preserved
por: Jo Cutler, et al.
Publicado: (2021) -
TaiNi: Maximizing research output whilst improving animals’ welfare in neurophysiology experiments
por: Zhou Jiang, et al.
Publicado: (2017) -
The decoy SNARE Tomosyn sets tonic versus phasic release properties and is required for homeostatic synaptic plasticity
por: Chad W Sauvola, et al.
Publicado: (2021)