Molecular decoy to the Y-box binding protein-1 suppresses the growth of breast and prostate cancer cells whilst sparing normal cell viability.

The Y-box binding protein-1 (YB-1) is an oncogenic transcription/translation factor that is activated by phosphorylation at S102 whereby it induces the expression of growth promoting genes such as EGFR and HER-2. We recently illustrated by an in vitro kinase assay that a novel peptide to YB-1 was hi...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Jennifer H Law, Yvonne Li, Karen To, Michelle Wang, Arezoo Astanehe, Karen Lambie, Jaspreet Dhillon, Steven J M Jones, Martin E Gleave, Connie J Eaves, Sandra E Dunn
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2010
Materias:
R
Q
Acceso en línea:https://doaj.org/article/3147afe5871e4fafa2b7c7e078bf833e
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares