PLATELET ANTIAGGREGANTS: MECHANISMS OF ACTION AND USE ASOCIED RISKS

Cardiovascular diseases are the main cause of death in the world. Next to efforts to reduce the cardiovascular risk factors, several drugs are resorted to decrease morbimortality associated to these diseases: antihypertensive, antidiabetic, hypolipemiant and platelet antiaggregant drugs are used amo...

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Autores principales: Iván F. PALOMO G, Constanza I. TORRES U., Rodrigo E. MOORE-Carrasco., Marcelo A. ALARCÓN L., Patricio J. MARAGAÑO L.
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Publicado: Universidad de Antioquia 2009
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Acceso en línea:https://doaj.org/article/31500303069f477ca93935deba6ecb97
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spelling oai:doaj.org-article:31500303069f477ca93935deba6ecb972021-11-19T04:16:03ZPLATELET ANTIAGGREGANTS: MECHANISMS OF ACTION AND USE ASOCIED RISKS0121-40042145-2660https://doaj.org/article/31500303069f477ca93935deba6ecb972009-05-01T00:00:00Zhttps://revistas.udea.edu.co/index.php/vitae/article/view/1435https://doaj.org/toc/0121-4004https://doaj.org/toc/2145-2660Cardiovascular diseases are the main cause of death in the world. Next to efforts to reduce the cardiovascular risk factors, several drugs are resorted to decrease morbimortality associated to these diseases: antihypertensive, antidiabetic, hypolipemiant and platelet antiaggregant drugs are used among others. Due to the participation of platelets, not only in the early stages of the atherogenesis but also in the artery thromboses, the use of platelet antiaggregant drugs is very relevant in the primary and secondary prevention of the artery thrombosis. In this review, after a brief description of the primary hemostasis, aspects of antiplatelet like mechanisms of action and use asocied risks during the last 10 years are adressed. Primarily literature source was www.pubmed.com. The terms used in the search were: platelet antiaggregant, aspirin, dipyridamole, clopidogrel, abciximab, among others, then we searched the full texts of articles of interest and also used some hematology books. Iván F. PALOMO GConstanza I. TORRES U.Rodrigo E. MOORE-Carrasco.Marcelo A. ALARCÓN L.Patricio J. MARAGAÑO L.Universidad de Antioquiaarticleplatelet antiaggregantscardiovascular diseasesFood processing and manufactureTP368-456Pharmaceutical industryHD9665-9675ENVitae, Vol 16, Iss 1 (2009)
institution DOAJ
collection DOAJ
language EN
topic platelet antiaggregants
cardiovascular diseases
Food processing and manufacture
TP368-456
Pharmaceutical industry
HD9665-9675
spellingShingle platelet antiaggregants
cardiovascular diseases
Food processing and manufacture
TP368-456
Pharmaceutical industry
HD9665-9675
Iván F. PALOMO G
Constanza I. TORRES U.
Rodrigo E. MOORE-Carrasco.
Marcelo A. ALARCÓN L.
Patricio J. MARAGAÑO L.
PLATELET ANTIAGGREGANTS: MECHANISMS OF ACTION AND USE ASOCIED RISKS
description Cardiovascular diseases are the main cause of death in the world. Next to efforts to reduce the cardiovascular risk factors, several drugs are resorted to decrease morbimortality associated to these diseases: antihypertensive, antidiabetic, hypolipemiant and platelet antiaggregant drugs are used among others. Due to the participation of platelets, not only in the early stages of the atherogenesis but also in the artery thromboses, the use of platelet antiaggregant drugs is very relevant in the primary and secondary prevention of the artery thrombosis. In this review, after a brief description of the primary hemostasis, aspects of antiplatelet like mechanisms of action and use asocied risks during the last 10 years are adressed. Primarily literature source was www.pubmed.com. The terms used in the search were: platelet antiaggregant, aspirin, dipyridamole, clopidogrel, abciximab, among others, then we searched the full texts of articles of interest and also used some hematology books.
format article
author Iván F. PALOMO G
Constanza I. TORRES U.
Rodrigo E. MOORE-Carrasco.
Marcelo A. ALARCÓN L.
Patricio J. MARAGAÑO L.
author_facet Iván F. PALOMO G
Constanza I. TORRES U.
Rodrigo E. MOORE-Carrasco.
Marcelo A. ALARCÓN L.
Patricio J. MARAGAÑO L.
author_sort Iván F. PALOMO G
title PLATELET ANTIAGGREGANTS: MECHANISMS OF ACTION AND USE ASOCIED RISKS
title_short PLATELET ANTIAGGREGANTS: MECHANISMS OF ACTION AND USE ASOCIED RISKS
title_full PLATELET ANTIAGGREGANTS: MECHANISMS OF ACTION AND USE ASOCIED RISKS
title_fullStr PLATELET ANTIAGGREGANTS: MECHANISMS OF ACTION AND USE ASOCIED RISKS
title_full_unstemmed PLATELET ANTIAGGREGANTS: MECHANISMS OF ACTION AND USE ASOCIED RISKS
title_sort platelet antiaggregants: mechanisms of action and use asocied risks
publisher Universidad de Antioquia
publishDate 2009
url https://doaj.org/article/31500303069f477ca93935deba6ecb97
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