THE CLINICAL AND LABORATORY EFFECTIVENESS OF OSELTAMIVIR FOR TREATMENT OF INFLUENZA IN HOSPITALIZED PATIENTS

The goal of our study was to estimate the efficacy of antiviral drug Oseltamivir for influenza treatment. We assessed the effect of Oseltamivir on the immune status of the 75 patients. It was formed 2 groups of observations with confirmed diagnosis of influenza: 38 received therapy Oseltamivir and 3...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	L. V. Voloschcuk, E. G. Golovacheva, A. A. Go, A. L. Mushkatina, P. V. Zarishnuk, G. L. Dnieprovskay, T. L. Tumina
Formato:	article
Lenguaje:	RU
Publicado:	Sankt-Peterburg : NIIÈM imeni Pastera 2015
Materias:	flu cytokines intoxication syndrome catarrhal syndrome oseltamivir antiviral activity Infectious and parasitic diseases RC109-216
Acceso en línea:	https://doaj.org/article/3152b3334a414279950e7f35a3687437
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:3152b3334a414279950e7f35a3687437
record_format	dspace
spelling	oai:doaj.org-article:3152b3334a414279950e7f35a36874372021-11-22T07:09:47ZTHE CLINICAL AND LABORATORY EFFECTIVENESS OF OSELTAMIVIR FOR TREATMENT OF INFLUENZA IN HOSPITALIZED PATIENTS2220-76192313-739810.15789/2220-7619-2015-2-143-147https://doaj.org/article/3152b3334a414279950e7f35a36874372015-06-01T00:00:00Zhttps://www.iimmun.ru/iimm/article/view/295https://doaj.org/toc/2220-7619https://doaj.org/toc/2313-7398The goal of our study was to estimate the efficacy of antiviral drug Oseltamivir for influenza treatment. We assessed the effect of Oseltamivir on the immune status of the 75 patients. It was formed 2 groups of observations with confirmed diagnosis of influenza: 38 received therapy Oseltamivir and 37 people receiving pathogenetic treatment. Treatment Oseltamivir contributes to a significant reduction in the duration of the catarrhal and intoxication syndromes and prevents the development of complications and exacerbations of chronic disease in persons with modified backdrop premorbid, which indicates for its high antiviral activity. We can assume the effect of Oseltamivir for restore the disturbed balance of cytokines, on assessing the dynamics of IL-1β, IL-8, IFNα, IFNγ in the serum.L. V. VoloschcukE. G. GolovachevaA. A. GoA. L. MushkatinaP. V. ZarishnukG. L. DnieprovskayT. L. TuminaSankt-Peterburg : NIIÈM imeni Pasteraarticleflucytokinesintoxication syndromecatarrhal syndromeoseltamivirantiviral activityInfectious and parasitic diseasesRC109-216RUInfekciâ i Immunitet, Vol 5, Iss 2, Pp 143-147 (2015)
institution	DOAJ
collection	DOAJ
language	RU
topic	flu cytokines intoxication syndrome catarrhal syndrome oseltamivir antiviral activity Infectious and parasitic diseases RC109-216
spellingShingle	flu cytokines intoxication syndrome catarrhal syndrome oseltamivir antiviral activity Infectious and parasitic diseases RC109-216 L. V. Voloschcuk E. G. Golovacheva A. A. Go A. L. Mushkatina P. V. Zarishnuk G. L. Dnieprovskay T. L. Tumina THE CLINICAL AND LABORATORY EFFECTIVENESS OF OSELTAMIVIR FOR TREATMENT OF INFLUENZA IN HOSPITALIZED PATIENTS
description	The goal of our study was to estimate the efficacy of antiviral drug Oseltamivir for influenza treatment. We assessed the effect of Oseltamivir on the immune status of the 75 patients. It was formed 2 groups of observations with confirmed diagnosis of influenza: 38 received therapy Oseltamivir and 37 people receiving pathogenetic treatment. Treatment Oseltamivir contributes to a significant reduction in the duration of the catarrhal and intoxication syndromes and prevents the development of complications and exacerbations of chronic disease in persons with modified backdrop premorbid, which indicates for its high antiviral activity. We can assume the effect of Oseltamivir for restore the disturbed balance of cytokines, on assessing the dynamics of IL-1β, IL-8, IFNα, IFNγ in the serum.
format	article
author	L. V. Voloschcuk E. G. Golovacheva A. A. Go A. L. Mushkatina P. V. Zarishnuk G. L. Dnieprovskay T. L. Tumina
author_facet	L. V. Voloschcuk E. G. Golovacheva A. A. Go A. L. Mushkatina P. V. Zarishnuk G. L. Dnieprovskay T. L. Tumina
author_sort	L. V. Voloschcuk
title	THE CLINICAL AND LABORATORY EFFECTIVENESS OF OSELTAMIVIR FOR TREATMENT OF INFLUENZA IN HOSPITALIZED PATIENTS
title_short	THE CLINICAL AND LABORATORY EFFECTIVENESS OF OSELTAMIVIR FOR TREATMENT OF INFLUENZA IN HOSPITALIZED PATIENTS
title_full	THE CLINICAL AND LABORATORY EFFECTIVENESS OF OSELTAMIVIR FOR TREATMENT OF INFLUENZA IN HOSPITALIZED PATIENTS
title_fullStr	THE CLINICAL AND LABORATORY EFFECTIVENESS OF OSELTAMIVIR FOR TREATMENT OF INFLUENZA IN HOSPITALIZED PATIENTS
title_full_unstemmed	THE CLINICAL AND LABORATORY EFFECTIVENESS OF OSELTAMIVIR FOR TREATMENT OF INFLUENZA IN HOSPITALIZED PATIENTS
title_sort	clinical and laboratory effectiveness of oseltamivir for treatment of influenza in hospitalized patients
publisher	Sankt-Peterburg : NIIÈM imeni Pastera
publishDate	2015
url	https://doaj.org/article/3152b3334a414279950e7f35a3687437
work_keys_str_mv	AT lvvoloschcuk theclinicalandlaboratoryeffectivenessofoseltamivirfortreatmentofinfluenzainhospitalizedpatients AT eggolovacheva theclinicalandlaboratoryeffectivenessofoseltamivirfortreatmentofinfluenzainhospitalizedpatients AT aago theclinicalandlaboratoryeffectivenessofoseltamivirfortreatmentofinfluenzainhospitalizedpatients AT almushkatina theclinicalandlaboratoryeffectivenessofoseltamivirfortreatmentofinfluenzainhospitalizedpatients AT pvzarishnuk theclinicalandlaboratoryeffectivenessofoseltamivirfortreatmentofinfluenzainhospitalizedpatients AT gldnieprovskay theclinicalandlaboratoryeffectivenessofoseltamivirfortreatmentofinfluenzainhospitalizedpatients AT tltumina theclinicalandlaboratoryeffectivenessofoseltamivirfortreatmentofinfluenzainhospitalizedpatients AT lvvoloschcuk clinicalandlaboratoryeffectivenessofoseltamivirfortreatmentofinfluenzainhospitalizedpatients AT eggolovacheva clinicalandlaboratoryeffectivenessofoseltamivirfortreatmentofinfluenzainhospitalizedpatients AT aago clinicalandlaboratoryeffectivenessofoseltamivirfortreatmentofinfluenzainhospitalizedpatients AT almushkatina clinicalandlaboratoryeffectivenessofoseltamivirfortreatmentofinfluenzainhospitalizedpatients AT pvzarishnuk clinicalandlaboratoryeffectivenessofoseltamivirfortreatmentofinfluenzainhospitalizedpatients AT gldnieprovskay clinicalandlaboratoryeffectivenessofoseltamivirfortreatmentofinfluenzainhospitalizedpatients AT tltumina clinicalandlaboratoryeffectivenessofoseltamivirfortreatmentofinfluenzainhospitalizedpatients
_version_	1718418031932080128

THE CLINICAL AND LABORATORY EFFECTIVENESS OF OSELTAMIVIR FOR TREATMENT OF INFLUENZA IN HOSPITALIZED PATIENTS

Ejemplares similares