Functional in vitro assessment of modified antibodies: Impact of label on protein properties.
Labelling of therapeutic antibodies with radionuclides or fluorophores is routinely used to study their pharmacokinetic properties. A critical assumption in utilizing labelled therapeutic antibodies is that the label has no unfavourable effects on antibody charge, hydrophobicity, or receptor affinit...
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Autores principales: | Martin R Edelmann, Simon Hauri |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/315633afb252420586c82ff217f61f6b |
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