The Tnfaip8-PE complex is a novel upstream effector in the anti-autophagic action of insulin

Abstract Defective hepatic autophagy is observed in obesity and diabetes, whereas autophagy is inhibited by insulin in hepatocytes. Insulin-induced anti-autophagy is mediated by non-canonical Gαi3 signaling via an unknown mechanism. Previously, we identified the anti-autophagic activity of Tnfaip8 v...

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Autores principales: Ji-Soo Kim, Jimin Park, Mi-Sun Kim, Ji-Young Ha, Ye-Won Jang, Dong Hae Shin, Jin H. Son
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/31666f6e62154e0fb33f59d1326e8f05
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