The histone variant H2A.X is a regulator of the epithelial–mesenchymal transition
The histone H2A variants are involved in DNA repair, gene regulation and cancer development. In this study, the authors unravel an additional role for H2A.X in the regulation of mesenchymal-like traits and activation of the EMT transcription factors, Slug and ZEB1, in colon cancer cells.
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Nature Portfolio
2016
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oai:doaj.org-article:3167703fb83c4199980e307269ce14a02021-12-02T16:56:45ZThe histone variant H2A.X is a regulator of the epithelial–mesenchymal transition10.1038/ncomms107112041-1723https://doaj.org/article/3167703fb83c4199980e307269ce14a02016-02-01T00:00:00Zhttps://doi.org/10.1038/ncomms10711https://doaj.org/toc/2041-1723The histone H2A variants are involved in DNA repair, gene regulation and cancer development. In this study, the authors unravel an additional role for H2A.X in the regulation of mesenchymal-like traits and activation of the EMT transcription factors, Slug and ZEB1, in colon cancer cells.Urbain WeyemiChristophe E. RedonRohini ChoudhuriTowqir AzizDaisuke MaedaMyriem BoufraqechPalak R. ParekhTaresh K. SethiManjula KasojiNatalie AbramsAnand MerchantVinodh N. RajapakseWilliam M. BonnerNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-12 (2016) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Science Q |
| spellingShingle |
Science Q Urbain Weyemi Christophe E. Redon Rohini Choudhuri Towqir Aziz Daisuke Maeda Myriem Boufraqech Palak R. Parekh Taresh K. Sethi Manjula Kasoji Natalie Abrams Anand Merchant Vinodh N. Rajapakse William M. Bonner The histone variant H2A.X is a regulator of the epithelial–mesenchymal transition |
| description |
The histone H2A variants are involved in DNA repair, gene regulation and cancer development. In this study, the authors unravel an additional role for H2A.X in the regulation of mesenchymal-like traits and activation of the EMT transcription factors, Slug and ZEB1, in colon cancer cells. |
| format |
article |
| author |
Urbain Weyemi Christophe E. Redon Rohini Choudhuri Towqir Aziz Daisuke Maeda Myriem Boufraqech Palak R. Parekh Taresh K. Sethi Manjula Kasoji Natalie Abrams Anand Merchant Vinodh N. Rajapakse William M. Bonner |
| author_facet |
Urbain Weyemi Christophe E. Redon Rohini Choudhuri Towqir Aziz Daisuke Maeda Myriem Boufraqech Palak R. Parekh Taresh K. Sethi Manjula Kasoji Natalie Abrams Anand Merchant Vinodh N. Rajapakse William M. Bonner |
| author_sort |
Urbain Weyemi |
| title |
The histone variant H2A.X is a regulator of the epithelial–mesenchymal transition |
| title_short |
The histone variant H2A.X is a regulator of the epithelial–mesenchymal transition |
| title_full |
The histone variant H2A.X is a regulator of the epithelial–mesenchymal transition |
| title_fullStr |
The histone variant H2A.X is a regulator of the epithelial–mesenchymal transition |
| title_full_unstemmed |
The histone variant H2A.X is a regulator of the epithelial–mesenchymal transition |
| title_sort |
histone variant h2a.x is a regulator of the epithelial–mesenchymal transition |
| publisher |
Nature Portfolio |
| publishDate |
2016 |
| url |
https://doaj.org/article/3167703fb83c4199980e307269ce14a0 |
| work_keys_str_mv |
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