Downregulation of Rap1GAP Expression Activates the TGF-β/Smad3 Pathway to Inhibit the Expression of Sodium/Iodine Transporter in Papillary Thyroid Carcinoma Cells
Objective. Rap1GAP is considered a tumor suppressor gene, but its regulatory mechanism in papillary thyroid cancer (PTC) has not been clearly elucidated. The aim of this study was to explore whether the regulation between Rap1GAP and sodium/iodine transporter (NIS) in tumorigenesis of PTC is mediate...
Guardado en:
Autores principales: | Zheng Yan, Wang Yangyanqiu, Han Shuwen, Mao Jing, Liao Haihong, Chen Gong, Jin Yin, Zhou Qing, Gao Weili |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Hindawi Limited
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/316a40c1f0e14e458848e24890e223d6 |
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