Vital staining for cell death identifies Atg9a-dependent necrosis in developmental bone formation in mouse

Apoptosis occurs in numerous developmental processes but a role for necrosis in development is unclear. Here, the authors develop a detecting system of necrosis in the developing mouse and find a form of necrosis that is dependent on the autophagy-related gene Atg9a.

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Detalles Bibliográficos
Autores principales: Yusuke Imagawa, Tatsuya Saitoh, Yoshihide Tsujimoto
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/316c703746a4409ab2ce03a8f139d368
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Descripción
Sumario:Apoptosis occurs in numerous developmental processes but a role for necrosis in development is unclear. Here, the authors develop a detecting system of necrosis in the developing mouse and find a form of necrosis that is dependent on the autophagy-related gene Atg9a.