Prevalence of BRCA1 mutations in familial and sporadic greek ovarian cancer cases.

Germline mutations in the BRCA1 and BRCA2 genes contribute to approximately 18% of hereditary ovarian cancers conferring an estimated lifetime risk from 15% to 50%. A variable incidence of mutations has been reported for these genes in ovarian cancer cases from different populations. In Greece, six...

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Autores principales:	Alexandra V Stavropoulou, Florentia Fostira, Maroulio Pertesi, Marianthi Tsitlaidou, Gerassimos E Voutsinas, Olga Triantafyllidou, Aristotelis Bamias, Meletios A Dimopoulos, Eleni Timotheadou, Dimitrios Pectasides, Christos Christodoulou, George Klouvas, Christos Papadimitriou, Thomas Makatsoris, George Pentheroudakis, Gerasimos Aravantinos, Vassilis Karydakis, Drakoulis Yannoukakos, George Fountzilas, Irene Konstantopoulou
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2013
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/31776ac91b8e4660ae8787ad61d4f727
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Prevalence of BRCA1 mutations in familial and sporadic greek ovarian cancer cases.

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