Concatemeric Broccoli reduces mRNA stability and induces aggregates.

Concatemeric Broccoli reduces mRNA stability and induces aggregates.

Fluorogenic aptamers are an alternative to established methodology for real-time imaging of RNA transport and dynamics. We developed Broccoli-aptamer concatemers ranging from 4 to 128 substrate-binding site repeats and characterized their behavior fused to an mCherry-coding mRNA in transient transfe...

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Autores principales: Marco R Rink, Marisa A P Baptista, Felix J Flomm, Thomas Hennig, Adam W Whisnant, Natalia Wolf, Jürgen Seibel, Lars Dölken, Jens B Bosse
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2021
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/3179583d0e394143b1db375ef4588a2b
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