Concatemeric Broccoli reduces mRNA stability and induces aggregates.
Fluorogenic aptamers are an alternative to established methodology for real-time imaging of RNA transport and dynamics. We developed Broccoli-aptamer concatemers ranging from 4 to 128 substrate-binding site repeats and characterized their behavior fused to an mCherry-coding mRNA in transient transfe...
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Autores principales: | , , , , , , , , |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2021
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Acceso en línea: | https://doaj.org/article/3179583d0e394143b1db375ef4588a2b |
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