Type I J-domain NbMIP1 proteins are required for both Tobacco mosaic virus infection and plant innate immunity.

Tm-2² is a coiled coil-nucleotide binding-leucine rich repeat resistance protein that confers durable extreme resistance against Tomato mosaic virus (ToMV) and Tobacco mosaic virus (TMV) by recognizing the viral movement protein (MP). Here we report that the Nicotiana benthamiana J-domain MIP1 prote...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Yumei Du, Jinping Zhao, Tianyuan Chen, Qi Liu, Haili Zhang, Yan Wang, Yiguo Hong, Fangming Xiao, Ling Zhang, Qianhua Shen, Yule Liu
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2013
Materias:	Immunologic diseases. Allergy RC581-607 Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/3179e3ac9cc340acab1499d3fcf6d214
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:3179e3ac9cc340acab1499d3fcf6d214
record_format	dspace
spelling	oai:doaj.org-article:3179e3ac9cc340acab1499d3fcf6d2142021-11-18T06:07:34ZType I J-domain NbMIP1 proteins are required for both Tobacco mosaic virus infection and plant innate immunity.1553-73661553-737410.1371/journal.ppat.1003659https://doaj.org/article/3179e3ac9cc340acab1499d3fcf6d2142013-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24098120/?tool=EBIhttps://doaj.org/toc/1553-7366https://doaj.org/toc/1553-7374Tm-2² is a coiled coil-nucleotide binding-leucine rich repeat resistance protein that confers durable extreme resistance against Tomato mosaic virus (ToMV) and Tobacco mosaic virus (TMV) by recognizing the viral movement protein (MP). Here we report that the Nicotiana benthamiana J-domain MIP1 proteins (NbMIP1s) associate with tobamovirus MP, Tm-2² and SGT1. Silencing of NbMIP1s reduced TMV movement and compromised Tm-2²-mediated resistance against TMV and ToMV. Furthermore, silencing of NbMIP1s reduced the steady-state protein levels of ToMV MP and Tm-2². Moreover, NbMIP1s are required for plant resistance induced by other R genes and the nonhost pathogen Pseudomonas syringae pv. tomato (Pst) DC3000. In addition, we found that SGT1 associates with Tm-2² and is required for Tm-2²-mediated resistance against TMV. These results suggest that NbMIP1s function as co-chaperones during virus infection and plant immunity.Yumei DuJinping ZhaoTianyuan ChenQi LiuHaili ZhangYan WangYiguo HongFangming XiaoLing ZhangQianhua ShenYule LiuPublic Library of Science (PLoS)articleImmunologic diseases. AllergyRC581-607Biology (General)QH301-705.5ENPLoS Pathogens, Vol 9, Iss 10, p e1003659 (2013)
institution	DOAJ
collection	DOAJ
language	EN
topic	Immunologic diseases. Allergy RC581-607 Biology (General) QH301-705.5
spellingShingle	Immunologic diseases. Allergy RC581-607 Biology (General) QH301-705.5 Yumei Du Jinping Zhao Tianyuan Chen Qi Liu Haili Zhang Yan Wang Yiguo Hong Fangming Xiao Ling Zhang Qianhua Shen Yule Liu Type I J-domain NbMIP1 proteins are required for both Tobacco mosaic virus infection and plant innate immunity.
description	Tm-2² is a coiled coil-nucleotide binding-leucine rich repeat resistance protein that confers durable extreme resistance against Tomato mosaic virus (ToMV) and Tobacco mosaic virus (TMV) by recognizing the viral movement protein (MP). Here we report that the Nicotiana benthamiana J-domain MIP1 proteins (NbMIP1s) associate with tobamovirus MP, Tm-2² and SGT1. Silencing of NbMIP1s reduced TMV movement and compromised Tm-2²-mediated resistance against TMV and ToMV. Furthermore, silencing of NbMIP1s reduced the steady-state protein levels of ToMV MP and Tm-2². Moreover, NbMIP1s are required for plant resistance induced by other R genes and the nonhost pathogen Pseudomonas syringae pv. tomato (Pst) DC3000. In addition, we found that SGT1 associates with Tm-2² and is required for Tm-2²-mediated resistance against TMV. These results suggest that NbMIP1s function as co-chaperones during virus infection and plant immunity.
format	article
author	Yumei Du Jinping Zhao Tianyuan Chen Qi Liu Haili Zhang Yan Wang Yiguo Hong Fangming Xiao Ling Zhang Qianhua Shen Yule Liu
author_facet	Yumei Du Jinping Zhao Tianyuan Chen Qi Liu Haili Zhang Yan Wang Yiguo Hong Fangming Xiao Ling Zhang Qianhua Shen Yule Liu
author_sort	Yumei Du
title	Type I J-domain NbMIP1 proteins are required for both Tobacco mosaic virus infection and plant innate immunity.
title_short	Type I J-domain NbMIP1 proteins are required for both Tobacco mosaic virus infection and plant innate immunity.
title_full	Type I J-domain NbMIP1 proteins are required for both Tobacco mosaic virus infection and plant innate immunity.
title_fullStr	Type I J-domain NbMIP1 proteins are required for both Tobacco mosaic virus infection and plant innate immunity.
title_full_unstemmed	Type I J-domain NbMIP1 proteins are required for both Tobacco mosaic virus infection and plant innate immunity.
title_sort	type i j-domain nbmip1 proteins are required for both tobacco mosaic virus infection and plant innate immunity.
publisher	Public Library of Science (PLoS)
publishDate	2013
url	https://doaj.org/article/3179e3ac9cc340acab1499d3fcf6d214
work_keys_str_mv	AT yumeidu typeijdomainnbmip1proteinsarerequiredforbothtobaccomosaicvirusinfectionandplantinnateimmunity AT jinpingzhao typeijdomainnbmip1proteinsarerequiredforbothtobaccomosaicvirusinfectionandplantinnateimmunity AT tianyuanchen typeijdomainnbmip1proteinsarerequiredforbothtobaccomosaicvirusinfectionandplantinnateimmunity AT qiliu typeijdomainnbmip1proteinsarerequiredforbothtobaccomosaicvirusinfectionandplantinnateimmunity AT hailizhang typeijdomainnbmip1proteinsarerequiredforbothtobaccomosaicvirusinfectionandplantinnateimmunity AT yanwang typeijdomainnbmip1proteinsarerequiredforbothtobaccomosaicvirusinfectionandplantinnateimmunity AT yiguohong typeijdomainnbmip1proteinsarerequiredforbothtobaccomosaicvirusinfectionandplantinnateimmunity AT fangmingxiao typeijdomainnbmip1proteinsarerequiredforbothtobaccomosaicvirusinfectionandplantinnateimmunity AT lingzhang typeijdomainnbmip1proteinsarerequiredforbothtobaccomosaicvirusinfectionandplantinnateimmunity AT qianhuashen typeijdomainnbmip1proteinsarerequiredforbothtobaccomosaicvirusinfectionandplantinnateimmunity AT yuleliu typeijdomainnbmip1proteinsarerequiredforbothtobaccomosaicvirusinfectionandplantinnateimmunity
_version_	1718424527384346624

Type I J-domain NbMIP1 proteins are required for both Tobacco mosaic virus infection and plant innate immunity.

Ejemplares similares