Dormant spores sense amino acids through the B subunits of their germination receptors

Germination of Bacillus subtilis spores in response to L-alanine requires a putative membrane receptor consisting of three proteins. Here, Artzi et al. use evolutionary co-variation analysis and functional assays of mutants to provide evidence that one of the proteins, GerAB, likely acts as the L-al...

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Autores principales: Lior Artzi, Assaf Alon, Kelly P. Brock, Anna G. Green, Amy Tam, Fernando H. Ramírez-Guadiana, Debora Marks, Andrew Kruse, David Z. Rudner
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/317baf2269254630a91f1d819120ed76
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Sumario:Germination of Bacillus subtilis spores in response to L-alanine requires a putative membrane receptor consisting of three proteins. Here, Artzi et al. use evolutionary co-variation analysis and functional assays of mutants to provide evidence that one of the proteins, GerAB, likely acts as the L-alanine sensor.