Dormant spores sense amino acids through the B subunits of their germination receptors
Germination of Bacillus subtilis spores in response to L-alanine requires a putative membrane receptor consisting of three proteins. Here, Artzi et al. use evolutionary co-variation analysis and functional assays of mutants to provide evidence that one of the proteins, GerAB, likely acts as the L-al...
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Nature Portfolio
2021
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oai:doaj.org-article:317baf2269254630a91f1d819120ed762021-11-28T12:32:33ZDormant spores sense amino acids through the B subunits of their germination receptors10.1038/s41467-021-27235-22041-1723https://doaj.org/article/317baf2269254630a91f1d819120ed762021-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-27235-2https://doaj.org/toc/2041-1723Germination of Bacillus subtilis spores in response to L-alanine requires a putative membrane receptor consisting of three proteins. Here, Artzi et al. use evolutionary co-variation analysis and functional assays of mutants to provide evidence that one of the proteins, GerAB, likely acts as the L-alanine sensor.Lior ArtziAssaf AlonKelly P. BrockAnna G. GreenAmy TamFernando H. Ramírez-GuadianaDebora MarksAndrew KruseDavid Z. RudnerNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-8 (2021) |
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Science Q Lior Artzi Assaf Alon Kelly P. Brock Anna G. Green Amy Tam Fernando H. Ramírez-Guadiana Debora Marks Andrew Kruse David Z. Rudner Dormant spores sense amino acids through the B subunits of their germination receptors |
description |
Germination of Bacillus subtilis spores in response to L-alanine requires a putative membrane receptor consisting of three proteins. Here, Artzi et al. use evolutionary co-variation analysis and functional assays of mutants to provide evidence that one of the proteins, GerAB, likely acts as the L-alanine sensor. |
format |
article |
author |
Lior Artzi Assaf Alon Kelly P. Brock Anna G. Green Amy Tam Fernando H. Ramírez-Guadiana Debora Marks Andrew Kruse David Z. Rudner |
author_facet |
Lior Artzi Assaf Alon Kelly P. Brock Anna G. Green Amy Tam Fernando H. Ramírez-Guadiana Debora Marks Andrew Kruse David Z. Rudner |
author_sort |
Lior Artzi |
title |
Dormant spores sense amino acids through the B subunits of their germination receptors |
title_short |
Dormant spores sense amino acids through the B subunits of their germination receptors |
title_full |
Dormant spores sense amino acids through the B subunits of their germination receptors |
title_fullStr |
Dormant spores sense amino acids through the B subunits of their germination receptors |
title_full_unstemmed |
Dormant spores sense amino acids through the B subunits of their germination receptors |
title_sort |
dormant spores sense amino acids through the b subunits of their germination receptors |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/317baf2269254630a91f1d819120ed76 |
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