Dormant spores sense amino acids through the B subunits of their germination receptors

Germination of Bacillus subtilis spores in response to L-alanine requires a putative membrane receptor consisting of three proteins. Here, Artzi et al. use evolutionary co-variation analysis and functional assays of mutants to provide evidence that one of the proteins, GerAB, likely acts as the L-al...

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Autores principales: Lior Artzi, Assaf Alon, Kelly P. Brock, Anna G. Green, Amy Tam, Fernando H. Ramírez-Guadiana, Debora Marks, Andrew Kruse, David Z. Rudner
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/317baf2269254630a91f1d819120ed76
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spelling oai:doaj.org-article:317baf2269254630a91f1d819120ed762021-11-28T12:32:33ZDormant spores sense amino acids through the B subunits of their germination receptors10.1038/s41467-021-27235-22041-1723https://doaj.org/article/317baf2269254630a91f1d819120ed762021-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-27235-2https://doaj.org/toc/2041-1723Germination of Bacillus subtilis spores in response to L-alanine requires a putative membrane receptor consisting of three proteins. Here, Artzi et al. use evolutionary co-variation analysis and functional assays of mutants to provide evidence that one of the proteins, GerAB, likely acts as the L-alanine sensor.Lior ArtziAssaf AlonKelly P. BrockAnna G. GreenAmy TamFernando H. Ramírez-GuadianaDebora MarksAndrew KruseDavid Z. RudnerNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-8 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Lior Artzi
Assaf Alon
Kelly P. Brock
Anna G. Green
Amy Tam
Fernando H. Ramírez-Guadiana
Debora Marks
Andrew Kruse
David Z. Rudner
Dormant spores sense amino acids through the B subunits of their germination receptors
description Germination of Bacillus subtilis spores in response to L-alanine requires a putative membrane receptor consisting of three proteins. Here, Artzi et al. use evolutionary co-variation analysis and functional assays of mutants to provide evidence that one of the proteins, GerAB, likely acts as the L-alanine sensor.
format article
author Lior Artzi
Assaf Alon
Kelly P. Brock
Anna G. Green
Amy Tam
Fernando H. Ramírez-Guadiana
Debora Marks
Andrew Kruse
David Z. Rudner
author_facet Lior Artzi
Assaf Alon
Kelly P. Brock
Anna G. Green
Amy Tam
Fernando H. Ramírez-Guadiana
Debora Marks
Andrew Kruse
David Z. Rudner
author_sort Lior Artzi
title Dormant spores sense amino acids through the B subunits of their germination receptors
title_short Dormant spores sense amino acids through the B subunits of their germination receptors
title_full Dormant spores sense amino acids through the B subunits of their germination receptors
title_fullStr Dormant spores sense amino acids through the B subunits of their germination receptors
title_full_unstemmed Dormant spores sense amino acids through the B subunits of their germination receptors
title_sort dormant spores sense amino acids through the b subunits of their germination receptors
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/317baf2269254630a91f1d819120ed76
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