Construction of a new luminescent Cd(ii) compound for the detection of Fe3+ and treatment of Hepatitis B
A novel porous Cd(ii) metal–organic framework (MOF) with the chemical composition of {[H3O][Cd(bci)]}n·2n(H2O) (1, H3bci = bis(2-carboxyethyl)isocyanurate) was prepared via hydrothermal responses of H3bci and Cd(NO3)2·4H2O. Luminescent property investigations indicated that compound 1 had high sensi...
Guardado en:
| Autores principales: | , |
|---|---|
| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
De Gruyter
2021
|
| Materias: | |
| Acceso en línea: | https://doaj.org/article/318aa7868a7b49caa7ad465fdd284c99 |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| id |
oai:doaj.org-article:318aa7868a7b49caa7ad465fdd284c99 |
|---|---|
| record_format |
dspace |
| spelling |
oai:doaj.org-article:318aa7868a7b49caa7ad465fdd284c992021-12-05T14:10:44ZConstruction of a new luminescent Cd(ii) compound for the detection of Fe3+ and treatment of Hepatitis B2391-542010.1515/chem-2021-0085https://doaj.org/article/318aa7868a7b49caa7ad465fdd284c992021-09-01T00:00:00Zhttps://doi.org/10.1515/chem-2021-0085https://doaj.org/toc/2391-5420A novel porous Cd(ii) metal–organic framework (MOF) with the chemical composition of {[H3O][Cd(bci)]}n·2n(H2O) (1, H3bci = bis(2-carboxyethyl)isocyanurate) was prepared via hydrothermal responses of H3bci and Cd(NO3)2·4H2O. Luminescent property investigations indicated that compound 1 had high sensitivity toward Fe3+, and the detection limit of Fe3+ was as low as 2.15 × 10−4 M. The application values of Fe3+ on Hepatitis B were assessed, and its associated mechanism was identified simultaneously. First, the cytotoxic mediator (TNF-α) substance released into plasma was measured through the ELISA. In addition, real-time RT-PCR was employed to determine the Hepatitis B viral replication gene relative expression levels. Finally, the novel compound’s toxicity against human normal liver cells was tested by using the CCK-8 assay.Huang Min-MinXu Li-NaDe Gruyterarticlecd(ii) compoundporous frameworkluminescence sensinghepatitis btoxicityChemistryQD1-999ENOpen Chemistry, Vol 19, Iss 1, Pp 953-960 (2021) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
cd(ii) compound porous framework luminescence sensing hepatitis b toxicity Chemistry QD1-999 |
| spellingShingle |
cd(ii) compound porous framework luminescence sensing hepatitis b toxicity Chemistry QD1-999 Huang Min-Min Xu Li-Na Construction of a new luminescent Cd(ii) compound for the detection of Fe3+ and treatment of Hepatitis B |
| description |
A novel porous Cd(ii) metal–organic framework (MOF) with the chemical composition of {[H3O][Cd(bci)]}n·2n(H2O) (1, H3bci = bis(2-carboxyethyl)isocyanurate) was prepared via hydrothermal responses of H3bci and Cd(NO3)2·4H2O. Luminescent property investigations indicated that compound 1 had high sensitivity toward Fe3+, and the detection limit of Fe3+ was as low as 2.15 × 10−4 M. The application values of Fe3+ on Hepatitis B were assessed, and its associated mechanism was identified simultaneously. First, the cytotoxic mediator (TNF-α) substance released into plasma was measured through the ELISA. In addition, real-time RT-PCR was employed to determine the Hepatitis B viral replication gene relative expression levels. Finally, the novel compound’s toxicity against human normal liver cells was tested by using the CCK-8 assay. |
| format |
article |
| author |
Huang Min-Min Xu Li-Na |
| author_facet |
Huang Min-Min Xu Li-Na |
| author_sort |
Huang Min-Min |
| title |
Construction of a new luminescent Cd(ii) compound for the detection of Fe3+ and treatment of Hepatitis B |
| title_short |
Construction of a new luminescent Cd(ii) compound for the detection of Fe3+ and treatment of Hepatitis B |
| title_full |
Construction of a new luminescent Cd(ii) compound for the detection of Fe3+ and treatment of Hepatitis B |
| title_fullStr |
Construction of a new luminescent Cd(ii) compound for the detection of Fe3+ and treatment of Hepatitis B |
| title_full_unstemmed |
Construction of a new luminescent Cd(ii) compound for the detection of Fe3+ and treatment of Hepatitis B |
| title_sort |
construction of a new luminescent cd(ii) compound for the detection of fe3+ and treatment of hepatitis b |
| publisher |
De Gruyter |
| publishDate |
2021 |
| url |
https://doaj.org/article/318aa7868a7b49caa7ad465fdd284c99 |
| work_keys_str_mv |
AT huangminmin constructionofanewluminescentcdiicompoundforthedetectionoffe3andtreatmentofhepatitisb AT xulina constructionofanewluminescentcdiicompoundforthedetectionoffe3andtreatmentofhepatitisb |
| _version_ |
1718371781923831808 |