M1 Macrophage and M1/M2 ratio defined by transcriptomic signatures resemble only part of their conventional clinical characteristics in breast cancer

Abstract Tumor associated macrophages (TAMs) play a critical role in biology of various cancers, including breast cancer. In the current study, we defined “M1” macrophage and “M1”/“M2” ratio by transcriptomic signatures using xCell. We investigated the association between high level of “M1” macropha...

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Autores principales: Masanori Oshi, Yoshihisa Tokumaru, Mariko Asaoka, Li Yan, Vikas Satyananda, Ryusei Matsuyama, Nobuhisa Matsuhashi, Manabu Futamura, Takashi Ishikawa, Kazuhiro Yoshida, Itaru Endo, Kazuaki Takabe
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/318de2ecfd984b2d809073b5c0d913ba
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