Bacterial variability in the mammalian gut captured by a single-cell synthetic oscillator

Synthetic gene oscillators can be used to control timed function and periodic expression of genes. Here the authors demonstrate in vivo implementation in the mammalian gut that can keep time over several days.

Guardado en:
Detalles Bibliográficos
Autores principales: David T. Riglar, David L. Richmond, Laurent Potvin-Trottier, Andrew A. Verdegaal, Alexander D. Naydich, Somenath Bakshi, Emanuele Leoncini, Lorena G. Lyon, Johan Paulsson, Pamela A. Silver
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
Materias:
Q
Acceso en línea:https://doaj.org/article/318e46930f814075b90ecd9d069da686
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:318e46930f814075b90ecd9d069da686
record_format dspace
spelling oai:doaj.org-article:318e46930f814075b90ecd9d069da6862021-12-02T17:33:23ZBacterial variability in the mammalian gut captured by a single-cell synthetic oscillator10.1038/s41467-019-12638-z2041-1723https://doaj.org/article/318e46930f814075b90ecd9d069da6862019-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12638-zhttps://doaj.org/toc/2041-1723Synthetic gene oscillators can be used to control timed function and periodic expression of genes. Here the authors demonstrate in vivo implementation in the mammalian gut that can keep time over several days.David T. RiglarDavid L. RichmondLaurent Potvin-TrottierAndrew A. VerdegaalAlexander D. NaydichSomenath BakshiEmanuele LeonciniLorena G. LyonJohan PaulssonPamela A. SilverNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
David T. Riglar
David L. Richmond
Laurent Potvin-Trottier
Andrew A. Verdegaal
Alexander D. Naydich
Somenath Bakshi
Emanuele Leoncini
Lorena G. Lyon
Johan Paulsson
Pamela A. Silver
Bacterial variability in the mammalian gut captured by a single-cell synthetic oscillator
description Synthetic gene oscillators can be used to control timed function and periodic expression of genes. Here the authors demonstrate in vivo implementation in the mammalian gut that can keep time over several days.
format article
author David T. Riglar
David L. Richmond
Laurent Potvin-Trottier
Andrew A. Verdegaal
Alexander D. Naydich
Somenath Bakshi
Emanuele Leoncini
Lorena G. Lyon
Johan Paulsson
Pamela A. Silver
author_facet David T. Riglar
David L. Richmond
Laurent Potvin-Trottier
Andrew A. Verdegaal
Alexander D. Naydich
Somenath Bakshi
Emanuele Leoncini
Lorena G. Lyon
Johan Paulsson
Pamela A. Silver
author_sort David T. Riglar
title Bacterial variability in the mammalian gut captured by a single-cell synthetic oscillator
title_short Bacterial variability in the mammalian gut captured by a single-cell synthetic oscillator
title_full Bacterial variability in the mammalian gut captured by a single-cell synthetic oscillator
title_fullStr Bacterial variability in the mammalian gut captured by a single-cell synthetic oscillator
title_full_unstemmed Bacterial variability in the mammalian gut captured by a single-cell synthetic oscillator
title_sort bacterial variability in the mammalian gut captured by a single-cell synthetic oscillator
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/318e46930f814075b90ecd9d069da686
work_keys_str_mv AT davidtriglar bacterialvariabilityinthemammaliangutcapturedbyasinglecellsyntheticoscillator
AT davidlrichmond bacterialvariabilityinthemammaliangutcapturedbyasinglecellsyntheticoscillator
AT laurentpotvintrottier bacterialvariabilityinthemammaliangutcapturedbyasinglecellsyntheticoscillator
AT andrewaverdegaal bacterialvariabilityinthemammaliangutcapturedbyasinglecellsyntheticoscillator
AT alexanderdnaydich bacterialvariabilityinthemammaliangutcapturedbyasinglecellsyntheticoscillator
AT somenathbakshi bacterialvariabilityinthemammaliangutcapturedbyasinglecellsyntheticoscillator
AT emanueleleoncini bacterialvariabilityinthemammaliangutcapturedbyasinglecellsyntheticoscillator
AT lorenaglyon bacterialvariabilityinthemammaliangutcapturedbyasinglecellsyntheticoscillator
AT johanpaulsson bacterialvariabilityinthemammaliangutcapturedbyasinglecellsyntheticoscillator
AT pamelaasilver bacterialvariabilityinthemammaliangutcapturedbyasinglecellsyntheticoscillator
_version_ 1718379932323676160