Bacterial variability in the mammalian gut captured by a single-cell synthetic oscillator
Synthetic gene oscillators can be used to control timed function and periodic expression of genes. Here the authors demonstrate in vivo implementation in the mammalian gut that can keep time over several days.
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Nature Portfolio
2019
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oai:doaj.org-article:318e46930f814075b90ecd9d069da6862021-12-02T17:33:23ZBacterial variability in the mammalian gut captured by a single-cell synthetic oscillator10.1038/s41467-019-12638-z2041-1723https://doaj.org/article/318e46930f814075b90ecd9d069da6862019-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12638-zhttps://doaj.org/toc/2041-1723Synthetic gene oscillators can be used to control timed function and periodic expression of genes. Here the authors demonstrate in vivo implementation in the mammalian gut that can keep time over several days.David T. RiglarDavid L. RichmondLaurent Potvin-TrottierAndrew A. VerdegaalAlexander D. NaydichSomenath BakshiEmanuele LeonciniLorena G. LyonJohan PaulssonPamela A. SilverNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-12 (2019) |
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DOAJ |
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EN |
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Science Q |
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Science Q David T. Riglar David L. Richmond Laurent Potvin-Trottier Andrew A. Verdegaal Alexander D. Naydich Somenath Bakshi Emanuele Leoncini Lorena G. Lyon Johan Paulsson Pamela A. Silver Bacterial variability in the mammalian gut captured by a single-cell synthetic oscillator |
description |
Synthetic gene oscillators can be used to control timed function and periodic expression of genes. Here the authors demonstrate in vivo implementation in the mammalian gut that can keep time over several days. |
format |
article |
author |
David T. Riglar David L. Richmond Laurent Potvin-Trottier Andrew A. Verdegaal Alexander D. Naydich Somenath Bakshi Emanuele Leoncini Lorena G. Lyon Johan Paulsson Pamela A. Silver |
author_facet |
David T. Riglar David L. Richmond Laurent Potvin-Trottier Andrew A. Verdegaal Alexander D. Naydich Somenath Bakshi Emanuele Leoncini Lorena G. Lyon Johan Paulsson Pamela A. Silver |
author_sort |
David T. Riglar |
title |
Bacterial variability in the mammalian gut captured by a single-cell synthetic oscillator |
title_short |
Bacterial variability in the mammalian gut captured by a single-cell synthetic oscillator |
title_full |
Bacterial variability in the mammalian gut captured by a single-cell synthetic oscillator |
title_fullStr |
Bacterial variability in the mammalian gut captured by a single-cell synthetic oscillator |
title_full_unstemmed |
Bacterial variability in the mammalian gut captured by a single-cell synthetic oscillator |
title_sort |
bacterial variability in the mammalian gut captured by a single-cell synthetic oscillator |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/318e46930f814075b90ecd9d069da686 |
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