Two variants in the fibulin2 gene are associated with lower systolic blood pressure and decreased risk of hypertension.

Arterial stiffness is an important factor in hypertension. Fibulin 2 is an extracellular matrix scaffold protein involved in arterial stiffness and, hence, the fibulin 2 (FBLN2) gene may be a candidate for hypertension susceptibility. 4 single nucleotide polymorphisms (SNPs) of FBLN2 were evaluated...

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Autores principales: Joan-Carles Vallvé, Noemí Serra, Guillermo Zalba, Ana Fortuño, Oscar Beloqui, Raimon Ferre, Josep Ribalta, Lluís Masana
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/318f2a96b2874a3698e33f53fdbee6e1
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