BCAS2 is involved in alternative mRNA splicing in spermatogonia and the transition to meiosis

Breast cancer amplified sequence 2 (BCAS2) is involved in pre-mRNA splicing but its physiological role is unclear. Here, the authors find BCAS2 enriched in mice spermatogonia in the testes, and BCAS2 deletion in germ cells alters alternative splicing of spermatogenesis-related genes, causing male in...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Wenbo Liu, Fengchao Wang, Qianhua Xu, Junchao Shi, Xiaoxin Zhang, Xukun Lu, Zhen-Ao Zhao, Zheng Gao, Huaixiao Ma, Enkui Duan, Fei Gao, Shaorong Gao, Zhaohong Yi, Lei Li
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/318f4f53fb5a48d5adc1879ed3272619
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:318f4f53fb5a48d5adc1879ed3272619
record_format	dspace
spelling	oai:doaj.org-article:318f4f53fb5a48d5adc1879ed32726192021-12-02T14:42:17ZBCAS2 is involved in alternative mRNA splicing in spermatogonia and the transition to meiosis10.1038/ncomms141822041-1723https://doaj.org/article/318f4f53fb5a48d5adc1879ed32726192017-01-01T00:00:00Zhttps://doi.org/10.1038/ncomms14182https://doaj.org/toc/2041-1723Breast cancer amplified sequence 2 (BCAS2) is involved in pre-mRNA splicing but its physiological role is unclear. Here, the authors find BCAS2 enriched in mice spermatogonia in the testes, and BCAS2 deletion in germ cells alters alternative splicing of spermatogenesis-related genes, causing male infertility.Wenbo LiuFengchao WangQianhua XuJunchao ShiXiaoxin ZhangXukun LuZhen-Ao ZhaoZheng GaoHuaixiao MaEnkui DuanFei GaoShaorong GaoZhaohong YiLei LiNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Wenbo Liu Fengchao Wang Qianhua Xu Junchao Shi Xiaoxin Zhang Xukun Lu Zhen-Ao Zhao Zheng Gao Huaixiao Ma Enkui Duan Fei Gao Shaorong Gao Zhaohong Yi Lei Li BCAS2 is involved in alternative mRNA splicing in spermatogonia and the transition to meiosis
description	Breast cancer amplified sequence 2 (BCAS2) is involved in pre-mRNA splicing but its physiological role is unclear. Here, the authors find BCAS2 enriched in mice spermatogonia in the testes, and BCAS2 deletion in germ cells alters alternative splicing of spermatogenesis-related genes, causing male infertility.
format	article
author	Wenbo Liu Fengchao Wang Qianhua Xu Junchao Shi Xiaoxin Zhang Xukun Lu Zhen-Ao Zhao Zheng Gao Huaixiao Ma Enkui Duan Fei Gao Shaorong Gao Zhaohong Yi Lei Li
author_facet	Wenbo Liu Fengchao Wang Qianhua Xu Junchao Shi Xiaoxin Zhang Xukun Lu Zhen-Ao Zhao Zheng Gao Huaixiao Ma Enkui Duan Fei Gao Shaorong Gao Zhaohong Yi Lei Li
author_sort	Wenbo Liu
title	BCAS2 is involved in alternative mRNA splicing in spermatogonia and the transition to meiosis
title_short	BCAS2 is involved in alternative mRNA splicing in spermatogonia and the transition to meiosis
title_full	BCAS2 is involved in alternative mRNA splicing in spermatogonia and the transition to meiosis
title_fullStr	BCAS2 is involved in alternative mRNA splicing in spermatogonia and the transition to meiosis
title_full_unstemmed	BCAS2 is involved in alternative mRNA splicing in spermatogonia and the transition to meiosis
title_sort	bcas2 is involved in alternative mrna splicing in spermatogonia and the transition to meiosis
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/318f4f53fb5a48d5adc1879ed3272619
work_keys_str_mv	AT wenboliu bcas2isinvolvedinalternativemrnasplicinginspermatogoniaandthetransitiontomeiosis AT fengchaowang bcas2isinvolvedinalternativemrnasplicinginspermatogoniaandthetransitiontomeiosis AT qianhuaxu bcas2isinvolvedinalternativemrnasplicinginspermatogoniaandthetransitiontomeiosis AT junchaoshi bcas2isinvolvedinalternativemrnasplicinginspermatogoniaandthetransitiontomeiosis AT xiaoxinzhang bcas2isinvolvedinalternativemrnasplicinginspermatogoniaandthetransitiontomeiosis AT xukunlu bcas2isinvolvedinalternativemrnasplicinginspermatogoniaandthetransitiontomeiosis AT zhenaozhao bcas2isinvolvedinalternativemrnasplicinginspermatogoniaandthetransitiontomeiosis AT zhenggao bcas2isinvolvedinalternativemrnasplicinginspermatogoniaandthetransitiontomeiosis AT huaixiaoma bcas2isinvolvedinalternativemrnasplicinginspermatogoniaandthetransitiontomeiosis AT enkuiduan bcas2isinvolvedinalternativemrnasplicinginspermatogoniaandthetransitiontomeiosis AT feigao bcas2isinvolvedinalternativemrnasplicinginspermatogoniaandthetransitiontomeiosis AT shaoronggao bcas2isinvolvedinalternativemrnasplicinginspermatogoniaandthetransitiontomeiosis AT zhaohongyi bcas2isinvolvedinalternativemrnasplicinginspermatogoniaandthetransitiontomeiosis AT leili bcas2isinvolvedinalternativemrnasplicinginspermatogoniaandthetransitiontomeiosis
_version_	1718389742376058880

BCAS2 is involved in alternative mRNA splicing in spermatogonia and the transition to meiosis

Ejemplares similares