IMBALANCE OF IMMUNOREGULATORY Th1- AND Th2-CYTOKINES IN PERSISTENT VIRAL INFECTIONS
Abstract. The article is considering certain features of immunopathogenesis exhibited in persistent viral infections, taking into account modern data and recently introduced immunological techniques. It has been revealed that a long-term persistence of hepatitis B and C viruses, tick-borne encephali...
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2014
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oai:doaj.org-article:3190b2b7657c43cc846d6a6b238a145d2021-11-18T08:03:38ZIMBALANCE OF IMMUNOREGULATORY Th1- AND Th2-CYTOKINES IN PERSISTENT VIRAL INFECTIONS1563-06252313-741X10.15789/1563-0625-2007-1-53-60https://doaj.org/article/3190b2b7657c43cc846d6a6b238a145d2014-07-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/124https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XAbstract. The article is considering certain features of immunopathogenesis exhibited in persistent viral infections, taking into account modern data and recently introduced immunological techniques. It has been revealed that a long-term persistence of hepatitis B and C viruses, tick-borne encephalitis, and herpes simplex is accompanied by deficient functioning in the T-cell compartment of immune system, and by markedly altered production of immunoregulatory cytokines in peripheral blood mononuclear leukocytes, mainly characterized by Th2 predominance.I. O. NaslednikovaN. V. RyazantsevaV. V. NovitskyS. B. TkachenkoA. P. ZimaSPb RAACIarticleth1-lymphocytesth2-lymphocytescytokinesviral infectionsImmunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 9, Iss 1, Pp 53-60 (2014) |
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DOAJ |
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RU |
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th1-lymphocytes th2-lymphocytes cytokines viral infections Immunologic diseases. Allergy RC581-607 |
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th1-lymphocytes th2-lymphocytes cytokines viral infections Immunologic diseases. Allergy RC581-607 I. O. Naslednikova N. V. Ryazantseva V. V. Novitsky S. B. Tkachenko A. P. Zima IMBALANCE OF IMMUNOREGULATORY Th1- AND Th2-CYTOKINES IN PERSISTENT VIRAL INFECTIONS |
description |
Abstract. The article is considering certain features of immunopathogenesis exhibited in persistent viral infections, taking into account modern data and recently introduced immunological techniques. It has been revealed that a long-term persistence of hepatitis B and C viruses, tick-borne encephalitis, and herpes simplex is accompanied by deficient functioning in the T-cell compartment of immune system, and by markedly altered production of immunoregulatory cytokines in peripheral blood mononuclear leukocytes, mainly characterized by Th2 predominance. |
format |
article |
author |
I. O. Naslednikova N. V. Ryazantseva V. V. Novitsky S. B. Tkachenko A. P. Zima |
author_facet |
I. O. Naslednikova N. V. Ryazantseva V. V. Novitsky S. B. Tkachenko A. P. Zima |
author_sort |
I. O. Naslednikova |
title |
IMBALANCE OF IMMUNOREGULATORY Th1- AND Th2-CYTOKINES IN PERSISTENT VIRAL INFECTIONS |
title_short |
IMBALANCE OF IMMUNOREGULATORY Th1- AND Th2-CYTOKINES IN PERSISTENT VIRAL INFECTIONS |
title_full |
IMBALANCE OF IMMUNOREGULATORY Th1- AND Th2-CYTOKINES IN PERSISTENT VIRAL INFECTIONS |
title_fullStr |
IMBALANCE OF IMMUNOREGULATORY Th1- AND Th2-CYTOKINES IN PERSISTENT VIRAL INFECTIONS |
title_full_unstemmed |
IMBALANCE OF IMMUNOREGULATORY Th1- AND Th2-CYTOKINES IN PERSISTENT VIRAL INFECTIONS |
title_sort |
imbalance of immunoregulatory th1- and th2-cytokines in persistent viral infections |
publisher |
SPb RAACI |
publishDate |
2014 |
url |
https://doaj.org/article/3190b2b7657c43cc846d6a6b238a145d |
work_keys_str_mv |
AT ionaslednikova imbalanceofimmunoregulatoryth1andth2cytokinesinpersistentviralinfections AT nvryazantseva imbalanceofimmunoregulatoryth1andth2cytokinesinpersistentviralinfections AT vvnovitsky imbalanceofimmunoregulatoryth1andth2cytokinesinpersistentviralinfections AT sbtkachenko imbalanceofimmunoregulatoryth1andth2cytokinesinpersistentviralinfections AT apzima imbalanceofimmunoregulatoryth1andth2cytokinesinpersistentviralinfections |
_version_ |
1718422533992087552 |