IMBALANCE OF IMMUNOREGULATORY Th1- AND Th2-CYTOKINES IN PERSISTENT VIRAL INFECTIONS

Abstract. The article is considering certain features of immunopathogenesis exhibited in persistent viral infections, taking into account modern data and recently introduced immunological techniques. It has been revealed that a long-term persistence of hepatitis B and C viruses, tick-borne encephali...

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Autores principales: I. O. Naslednikova, N. V. Ryazantseva, V. V. Novitsky, S. B. Tkachenko, A. P. Zima
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Publicado: SPb RAACI 2014
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spelling oai:doaj.org-article:3190b2b7657c43cc846d6a6b238a145d2021-11-18T08:03:38ZIMBALANCE OF IMMUNOREGULATORY Th1- AND Th2-CYTOKINES IN PERSISTENT VIRAL INFECTIONS1563-06252313-741X10.15789/1563-0625-2007-1-53-60https://doaj.org/article/3190b2b7657c43cc846d6a6b238a145d2014-07-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/124https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XAbstract. The article is considering certain features of immunopathogenesis exhibited in persistent viral infections, taking into account modern data and recently introduced immunological techniques. It has been revealed that a long-term persistence of hepatitis B and C viruses, tick-borne encephalitis, and herpes simplex is accompanied by deficient functioning in the T-cell compartment of immune system, and by markedly altered production of immunoregulatory cytokines in peripheral blood mononuclear leukocytes, mainly characterized by Th2 predominance.I. O. NaslednikovaN. V. RyazantsevaV. V. NovitskyS. B. TkachenkoA. P. ZimaSPb RAACIarticleth1-lymphocytesth2-lymphocytescytokinesviral infectionsImmunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 9, Iss 1, Pp 53-60 (2014)
institution DOAJ
collection DOAJ
language RU
topic th1-lymphocytes
th2-lymphocytes
cytokines
viral infections
Immunologic diseases. Allergy
RC581-607
spellingShingle th1-lymphocytes
th2-lymphocytes
cytokines
viral infections
Immunologic diseases. Allergy
RC581-607
I. O. Naslednikova
N. V. Ryazantseva
V. V. Novitsky
S. B. Tkachenko
A. P. Zima
IMBALANCE OF IMMUNOREGULATORY Th1- AND Th2-CYTOKINES IN PERSISTENT VIRAL INFECTIONS
description Abstract. The article is considering certain features of immunopathogenesis exhibited in persistent viral infections, taking into account modern data and recently introduced immunological techniques. It has been revealed that a long-term persistence of hepatitis B and C viruses, tick-borne encephalitis, and herpes simplex is accompanied by deficient functioning in the T-cell compartment of immune system, and by markedly altered production of immunoregulatory cytokines in peripheral blood mononuclear leukocytes, mainly characterized by Th2 predominance.
format article
author I. O. Naslednikova
N. V. Ryazantseva
V. V. Novitsky
S. B. Tkachenko
A. P. Zima
author_facet I. O. Naslednikova
N. V. Ryazantseva
V. V. Novitsky
S. B. Tkachenko
A. P. Zima
author_sort I. O. Naslednikova
title IMBALANCE OF IMMUNOREGULATORY Th1- AND Th2-CYTOKINES IN PERSISTENT VIRAL INFECTIONS
title_short IMBALANCE OF IMMUNOREGULATORY Th1- AND Th2-CYTOKINES IN PERSISTENT VIRAL INFECTIONS
title_full IMBALANCE OF IMMUNOREGULATORY Th1- AND Th2-CYTOKINES IN PERSISTENT VIRAL INFECTIONS
title_fullStr IMBALANCE OF IMMUNOREGULATORY Th1- AND Th2-CYTOKINES IN PERSISTENT VIRAL INFECTIONS
title_full_unstemmed IMBALANCE OF IMMUNOREGULATORY Th1- AND Th2-CYTOKINES IN PERSISTENT VIRAL INFECTIONS
title_sort imbalance of immunoregulatory th1- and th2-cytokines in persistent viral infections
publisher SPb RAACI
publishDate 2014
url https://doaj.org/article/3190b2b7657c43cc846d6a6b238a145d
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AT nvryazantseva imbalanceofimmunoregulatoryth1andth2cytokinesinpersistentviralinfections
AT vvnovitsky imbalanceofimmunoregulatoryth1andth2cytokinesinpersistentviralinfections
AT sbtkachenko imbalanceofimmunoregulatoryth1andth2cytokinesinpersistentviralinfections
AT apzima imbalanceofimmunoregulatoryth1andth2cytokinesinpersistentviralinfections
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