Biomimetically inspired asymmetric total synthesis of (+)-19-dehydroxyl arisandilactone A
Arisandilactone A is a natural product with a complex oxa-bridged tricyclic carbon core, making it a challenging target in total synthesis. Here the authors report an asymmetric total synthesis of its 19-dehydroxy derivative, with homo-Michael and tandem retro-Michael/Michael reactions as key steps.
Guardado en:
Autores principales: | , , , , , , , , , , |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
|
Materias: | |
Acceso en línea: | https://doaj.org/article/319f43e19f6445e4882a30aa1bd31420 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
id |
oai:doaj.org-article:319f43e19f6445e4882a30aa1bd31420 |
---|---|
record_format |
dspace |
spelling |
oai:doaj.org-article:319f43e19f6445e4882a30aa1bd314202021-12-02T15:37:03ZBiomimetically inspired asymmetric total synthesis of (+)-19-dehydroxyl arisandilactone A10.1038/ncomms142332041-1723https://doaj.org/article/319f43e19f6445e4882a30aa1bd314202017-01-01T00:00:00Zhttps://doi.org/10.1038/ncomms14233https://doaj.org/toc/2041-1723Arisandilactone A is a natural product with a complex oxa-bridged tricyclic carbon core, making it a challenging target in total synthesis. Here the authors report an asymmetric total synthesis of its 19-dehydroxy derivative, with homo-Michael and tandem retro-Michael/Michael reactions as key steps.Yi-Xin HanYan-Long JiangYong LiHai-Xin YuBing-Qi TongZhe NiuShi-Jie ZhouSong LiuYu LanJia-Hua ChenZhen YangNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-13 (2017) |
institution |
DOAJ |
collection |
DOAJ |
language |
EN |
topic |
Science Q |
spellingShingle |
Science Q Yi-Xin Han Yan-Long Jiang Yong Li Hai-Xin Yu Bing-Qi Tong Zhe Niu Shi-Jie Zhou Song Liu Yu Lan Jia-Hua Chen Zhen Yang Biomimetically inspired asymmetric total synthesis of (+)-19-dehydroxyl arisandilactone A |
description |
Arisandilactone A is a natural product with a complex oxa-bridged tricyclic carbon core, making it a challenging target in total synthesis. Here the authors report an asymmetric total synthesis of its 19-dehydroxy derivative, with homo-Michael and tandem retro-Michael/Michael reactions as key steps. |
format |
article |
author |
Yi-Xin Han Yan-Long Jiang Yong Li Hai-Xin Yu Bing-Qi Tong Zhe Niu Shi-Jie Zhou Song Liu Yu Lan Jia-Hua Chen Zhen Yang |
author_facet |
Yi-Xin Han Yan-Long Jiang Yong Li Hai-Xin Yu Bing-Qi Tong Zhe Niu Shi-Jie Zhou Song Liu Yu Lan Jia-Hua Chen Zhen Yang |
author_sort |
Yi-Xin Han |
title |
Biomimetically inspired asymmetric total synthesis of (+)-19-dehydroxyl arisandilactone A |
title_short |
Biomimetically inspired asymmetric total synthesis of (+)-19-dehydroxyl arisandilactone A |
title_full |
Biomimetically inspired asymmetric total synthesis of (+)-19-dehydroxyl arisandilactone A |
title_fullStr |
Biomimetically inspired asymmetric total synthesis of (+)-19-dehydroxyl arisandilactone A |
title_full_unstemmed |
Biomimetically inspired asymmetric total synthesis of (+)-19-dehydroxyl arisandilactone A |
title_sort |
biomimetically inspired asymmetric total synthesis of (+)-19-dehydroxyl arisandilactone a |
publisher |
Nature Portfolio |
publishDate |
2017 |
url |
https://doaj.org/article/319f43e19f6445e4882a30aa1bd31420 |
work_keys_str_mv |
AT yixinhan biomimeticallyinspiredasymmetrictotalsynthesisof19dehydroxylarisandilactonea AT yanlongjiang biomimeticallyinspiredasymmetrictotalsynthesisof19dehydroxylarisandilactonea AT yongli biomimeticallyinspiredasymmetrictotalsynthesisof19dehydroxylarisandilactonea AT haixinyu biomimeticallyinspiredasymmetrictotalsynthesisof19dehydroxylarisandilactonea AT bingqitong biomimeticallyinspiredasymmetrictotalsynthesisof19dehydroxylarisandilactonea AT zheniu biomimeticallyinspiredasymmetrictotalsynthesisof19dehydroxylarisandilactonea AT shijiezhou biomimeticallyinspiredasymmetrictotalsynthesisof19dehydroxylarisandilactonea AT songliu biomimeticallyinspiredasymmetrictotalsynthesisof19dehydroxylarisandilactonea AT yulan biomimeticallyinspiredasymmetrictotalsynthesisof19dehydroxylarisandilactonea AT jiahuachen biomimeticallyinspiredasymmetrictotalsynthesisof19dehydroxylarisandilactonea AT zhenyang biomimeticallyinspiredasymmetrictotalsynthesisof19dehydroxylarisandilactonea |
_version_ |
1718386223492366336 |