MURC deficiency in smooth muscle attenuates pulmonary hypertension
MURC protein regulates the function of caveolae, the small invaginations of the plasma membrane in muscle cells. Here the authors show that by interacting with caveolin proteins, MURC affects RhoA/ROCK signalling and regulates proliferation and migration of pulmonary artery smooth muscle cells, sugg...
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Autores principales: | Naohiko Nakanishi, Takehiro Ogata, Daisuke Naito, Kotaro Miyagawa, Takuya Taniguchi, Tetsuro Hamaoka, Naoki Maruyama, Takeru Kasahara, Masahiro Nishi, Satoaki Matoba, Tomomi Ueyama |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2016
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Materias: | |
Acceso en línea: | https://doaj.org/article/319f57afca5f405fb6cd95e83c7e27fc |
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