MURC deficiency in smooth muscle attenuates pulmonary hypertension
MURC protein regulates the function of caveolae, the small invaginations of the plasma membrane in muscle cells. Here the authors show that by interacting with caveolin proteins, MURC affects RhoA/ROCK signalling and regulates proliferation and migration of pulmonary artery smooth muscle cells, sugg...
Enregistré dans:
Auteurs principaux: | Naohiko Nakanishi, Takehiro Ogata, Daisuke Naito, Kotaro Miyagawa, Takuya Taniguchi, Tetsuro Hamaoka, Naoki Maruyama, Takeru Kasahara, Masahiro Nishi, Satoaki Matoba, Tomomi Ueyama |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2016
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/319f57afca5f405fb6cd95e83c7e27fc |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
Asociación MURCS: reporte de caso
par: Saldarriaga,Wilmar, et autres
Publié: (2015) -
PARM-1 is an endoplasmic reticulum molecule involved in endoplasmic reticulum stress-induced apoptosis in rat cardiac myocytes.
par: Koji Isodono, et autres
Publié: (2010) -
Prediction of well-being and insight into work-life integration among physicians using machine learning approach.
par: Masahiro Nishi, et autres
Publié: (2021) -
Are Argonaute-Associated Tiny RNAs Junk, Inferior miRNAs, or a New Type of Functional RNAs?
par: Kotaro Nakanishi, et autres
Publié: (2021) -
Cellular senescence promotes endothelial activation through epigenetic alteration, and consequently accelerates atherosclerosis
par: Sakiko Honda, et autres
Publié: (2021)