The Glucocorticoid PYED-1 Disrupts Mature Biofilms of <i>Candida</i> spp. and Inhibits Hyphal Development in <i>Candida albicans</i>

The Glucocorticoid PYED-1 Disrupts Mature Biofilms of <i>Candida</i> spp. and Inhibits Hyphal Development in <i>Candida albicans</i>

Invasive <i>Candida</i> infections have become a global public health problem due to the increase of <i>Candida</i> species resistant against antifungal therapeutics. The glucocorticoid PYED-1 (pregnadiene-11-hydroxy-16α,17α-epoxy-3,20-dione-1) has antimicrobial activity agai...

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Bibliographic Details
Main Authors: Anna Esposito, Antonella Migliaccio, Vita Dora Iula, Raffaele Zarrilli, Annalisa Guaragna, Eliana De Gregorio
Format: article
Language:EN
Published: MDPI AG 2021
Subjects:
glucocorticoid
antifungal agents
anti-biofilm agents
<i>Candida</i> spp.
Therapeutics. Pharmacology
RM1-950
Online Access:https://doaj.org/article/31a1303f997247b89aec2c87c4219a2a
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https://doaj.org/article/31a1303f997247b89aec2c87c4219a2a

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