Amaurosis fugax: risk factors and prevalence of significant carotid stenosis

Pia Kvickström,1 Bertil Lindblom,2,3 Göran Bergström,4,5 Madeleine Zetterberg2,3 1Department of Ophthalmology, Skaraborg Hospital, Skövde, 2Department of Clinical Neuroscience/Ophthalmology, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at Uni...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Kvickström P, Lindblom B, Bergström G, Zetterberg M
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2016
Materias:	Amaurosis fugax Carotid stenosis Carotid ultrasound Giant cell arteritis Transient ischemic attack Transient monocular visual loss Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/31ae1964436f42f581e33ae75e0a5a2c
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:31ae1964436f42f581e33ae75e0a5a2c
record_format	dspace
spelling	oai:doaj.org-article:31ae1964436f42f581e33ae75e0a5a2c2021-12-02T02:27:58ZAmaurosis fugax: risk factors and prevalence of significant carotid stenosis1177-5483https://doaj.org/article/31ae1964436f42f581e33ae75e0a5a2c2016-10-01T00:00:00Zhttps://www.dovepress.com/amaurosis-fugax-risk-factors-and-prevalence-of-significant-carotid-ste-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Pia Kvickström,1 Bertil Lindblom,2,3 Göran Bergström,4,5 Madeleine Zetterberg2,3 1Department of Ophthalmology, Skaraborg Hospital, Skövde, 2Department of Clinical Neuroscience/Ophthalmology, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at University of Gothenburg, 3Department of Ophthalmology, Sahlgrenska University Hospital, Mölndal, 4Department of Molecular and Clinical Medicine, The Sahlgrenska Academy at University of Gothenburg, 5Department of Clinical Physiology, Sahlgrenska University Hospital, Gothenburg, Sweden Purpose: The purpose of this study was to describe clinical characteristics and prevalence of carotid stenosis in patients with amaurosis fugax (AF).Method: Patients diagnosed with AF and subjected to carotid ultrasound in 2004–2010 in Sahlgrenska University Hospital, Gothenburg (n=302), were included, and data were retrospectively collected from medical records.Results: The prevalence of significant carotid stenosis was 18.9%, and 14.2% of the subjects were subjected to carotid endarterectomy. Significant associations with risk of having ≥70% stenosis were male sex (adjusted odds ratio [aOR]: 2.62; 95% confidence interval [CI]: 1.26–5.46), current smoking (aOR: 6.26; 95% CI: 2.62–14.93), diabetes (aOR: 3.68; 95% CI: 1.37–9.90) and previous vasculitis (aOR: 10.78; 95% CI: 1.36–85.5). A majority of the patients (81.4%) was seen by an ophthalmologist prior to the first ultrasound. Only 1.7% of the patients exhibited retinal artery emboli at examination.Conclusion: The prevalence of carotid stenosis among patients with AF is higher than has previously been demonstrated in stroke patients. An association with previously reported vascular risk factors and with vasculitis is seen in this patient group. Ocular findings are scarce. Keywords: amaurosis fugax, carotid stenosis, carotid ultrasound, giant cell arteritis, transient ischemic attack, transient monocular visual lossKvickström PLindblom BBergström GZetterberg MDove Medical PressarticleAmaurosis fugaxCarotid stenosisCarotid ultrasoundGiant cell arteritisTransient ischemic attackTransient monocular visual lossOphthalmologyRE1-994ENClinical Ophthalmology, Vol Volume 10, Pp 2165-2170 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Amaurosis fugax Carotid stenosis Carotid ultrasound Giant cell arteritis Transient ischemic attack Transient monocular visual loss Ophthalmology RE1-994
spellingShingle	Amaurosis fugax Carotid stenosis Carotid ultrasound Giant cell arteritis Transient ischemic attack Transient monocular visual loss Ophthalmology RE1-994 Kvickström P Lindblom B Bergström G Zetterberg M Amaurosis fugax: risk factors and prevalence of significant carotid stenosis
description	Pia Kvickström,1 Bertil Lindblom,2,3 Göran Bergström,4,5 Madeleine Zetterberg2,3 1Department of Ophthalmology, Skaraborg Hospital, Skövde, 2Department of Clinical Neuroscience/Ophthalmology, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at University of Gothenburg, 3Department of Ophthalmology, Sahlgrenska University Hospital, Mölndal, 4Department of Molecular and Clinical Medicine, The Sahlgrenska Academy at University of Gothenburg, 5Department of Clinical Physiology, Sahlgrenska University Hospital, Gothenburg, Sweden Purpose: The purpose of this study was to describe clinical characteristics and prevalence of carotid stenosis in patients with amaurosis fugax (AF).Method: Patients diagnosed with AF and subjected to carotid ultrasound in 2004–2010 in Sahlgrenska University Hospital, Gothenburg (n=302), were included, and data were retrospectively collected from medical records.Results: The prevalence of significant carotid stenosis was 18.9%, and 14.2% of the subjects were subjected to carotid endarterectomy. Significant associations with risk of having ≥70% stenosis were male sex (adjusted odds ratio [aOR]: 2.62; 95% confidence interval [CI]: 1.26–5.46), current smoking (aOR: 6.26; 95% CI: 2.62–14.93), diabetes (aOR: 3.68; 95% CI: 1.37–9.90) and previous vasculitis (aOR: 10.78; 95% CI: 1.36–85.5). A majority of the patients (81.4%) was seen by an ophthalmologist prior to the first ultrasound. Only 1.7% of the patients exhibited retinal artery emboli at examination.Conclusion: The prevalence of carotid stenosis among patients with AF is higher than has previously been demonstrated in stroke patients. An association with previously reported vascular risk factors and with vasculitis is seen in this patient group. Ocular findings are scarce. Keywords: amaurosis fugax, carotid stenosis, carotid ultrasound, giant cell arteritis, transient ischemic attack, transient monocular visual loss
format	article
author	Kvickström P Lindblom B Bergström G Zetterberg M
author_facet	Kvickström P Lindblom B Bergström G Zetterberg M
author_sort	Kvickström P
title	Amaurosis fugax: risk factors and prevalence of significant carotid stenosis
title_short	Amaurosis fugax: risk factors and prevalence of significant carotid stenosis
title_full	Amaurosis fugax: risk factors and prevalence of significant carotid stenosis
title_fullStr	Amaurosis fugax: risk factors and prevalence of significant carotid stenosis
title_full_unstemmed	Amaurosis fugax: risk factors and prevalence of significant carotid stenosis
title_sort	amaurosis fugax: risk factors and prevalence of significant carotid stenosis
publisher	Dove Medical Press
publishDate	2016
url	https://doaj.org/article/31ae1964436f42f581e33ae75e0a5a2c
work_keys_str_mv	AT kvickstromp amaurosisfugaxriskfactorsandprevalenceofsignificantcarotidstenosis AT lindblomb amaurosisfugaxriskfactorsandprevalenceofsignificantcarotidstenosis AT bergstromg amaurosisfugaxriskfactorsandprevalenceofsignificantcarotidstenosis AT zetterbergm amaurosisfugaxriskfactorsandprevalenceofsignificantcarotidstenosis
_version_	1718402458691043328

Amaurosis fugax: risk factors and prevalence of significant carotid stenosis

Ejemplares similares