Design of Porous Metal Block Augmentation to Treat Tibial Bone Defects in Total Knee Arthroplasty Based on Topology Optimization

Metal block augmentation, which is used for the treatment of tibial bone defects in total knee arthroplasty, with high stiffness will cause significant alteration in stress distribution, and its solid structure is not suitable for osseointegration. This study aimed to design a porous block to reduce...

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Autores principales:	Yang Liu, Bingpeng Chen, Chenyu Wang, Hao Chen, Aobo Zhang, Weihuang Yin, Naichao Wu, Qing Han, Jincheng Wang
Formato:	article
Lenguaje:	EN
Publicado:	Frontiers Media S.A. 2021
Materias:	finite element analysis total knee arthroplasty topology optimization metal block augmentation bone defect Biotechnology TP248.13-248.65
Acceso en línea:	https://doaj.org/article/31b4deb9f35e46dca3a4ffef70fefc93
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spelling	oai:doaj.org-article:31b4deb9f35e46dca3a4ffef70fefc932021-11-08T06:29:22ZDesign of Porous Metal Block Augmentation to Treat Tibial Bone Defects in Total Knee Arthroplasty Based on Topology Optimization2296-418510.3389/fbioe.2021.765438https://doaj.org/article/31b4deb9f35e46dca3a4ffef70fefc932021-11-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fbioe.2021.765438/fullhttps://doaj.org/toc/2296-4185Metal block augmentation, which is used for the treatment of tibial bone defects in total knee arthroplasty, with high stiffness will cause significant alteration in stress distribution, and its solid structure is not suitable for osseointegration. This study aimed to design a porous block to reduce weight, promote bone ingrowth, and improve its biomechanical performance. The metal block augmentation technique was applied to finite element models of tibial bone defects. Minimum compliance topology optimization subject to volume fraction combined with the porous architecture was adopted to redesign the block. Biomechanical changes compared with the original block were analyzed by finite element analysis. The stress distribution of the block and proximal tibia was recorded. The strain energy density of the proximal tibia was obtained. The newly designed block realized 40% weight reduction. The maximum stress in the optimized block decreased by 11.6% when compared with the solid one. The maximum stress of the proximal tibia in the optimized group increased by 18.6%. The stress of the anterior, medial, and posterior parts of the proximal medial tibia in the optimized group was significantly greater than that in the original group (all p < 0.05). The optimized block could effectively improve the biomechanical performance between the block and the bone. The presented method might provide a reference for the design of customized three-dimensional printed prostheses.Yang LiuBingpeng ChenChenyu WangHao ChenAobo ZhangWeihuang YinNaichao WuQing HanJincheng WangFrontiers Media S.A.articlefinite element analysistotal knee arthroplastytopology optimizationmetal block augmentationbone defectBiotechnologyTP248.13-248.65ENFrontiers in Bioengineering and Biotechnology, Vol 9 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	finite element analysis total knee arthroplasty topology optimization metal block augmentation bone defect Biotechnology TP248.13-248.65
spellingShingle	finite element analysis total knee arthroplasty topology optimization metal block augmentation bone defect Biotechnology TP248.13-248.65 Yang Liu Bingpeng Chen Chenyu Wang Hao Chen Aobo Zhang Weihuang Yin Naichao Wu Qing Han Jincheng Wang Design of Porous Metal Block Augmentation to Treat Tibial Bone Defects in Total Knee Arthroplasty Based on Topology Optimization
description	Metal block augmentation, which is used for the treatment of tibial bone defects in total knee arthroplasty, with high stiffness will cause significant alteration in stress distribution, and its solid structure is not suitable for osseointegration. This study aimed to design a porous block to reduce weight, promote bone ingrowth, and improve its biomechanical performance. The metal block augmentation technique was applied to finite element models of tibial bone defects. Minimum compliance topology optimization subject to volume fraction combined with the porous architecture was adopted to redesign the block. Biomechanical changes compared with the original block were analyzed by finite element analysis. The stress distribution of the block and proximal tibia was recorded. The strain energy density of the proximal tibia was obtained. The newly designed block realized 40% weight reduction. The maximum stress in the optimized block decreased by 11.6% when compared with the solid one. The maximum stress of the proximal tibia in the optimized group increased by 18.6%. The stress of the anterior, medial, and posterior parts of the proximal medial tibia in the optimized group was significantly greater than that in the original group (all p < 0.05). The optimized block could effectively improve the biomechanical performance between the block and the bone. The presented method might provide a reference for the design of customized three-dimensional printed prostheses.
format	article
author	Yang Liu Bingpeng Chen Chenyu Wang Hao Chen Aobo Zhang Weihuang Yin Naichao Wu Qing Han Jincheng Wang
author_facet	Yang Liu Bingpeng Chen Chenyu Wang Hao Chen Aobo Zhang Weihuang Yin Naichao Wu Qing Han Jincheng Wang
author_sort	Yang Liu
title	Design of Porous Metal Block Augmentation to Treat Tibial Bone Defects in Total Knee Arthroplasty Based on Topology Optimization
title_short	Design of Porous Metal Block Augmentation to Treat Tibial Bone Defects in Total Knee Arthroplasty Based on Topology Optimization
title_full	Design of Porous Metal Block Augmentation to Treat Tibial Bone Defects in Total Knee Arthroplasty Based on Topology Optimization
title_fullStr	Design of Porous Metal Block Augmentation to Treat Tibial Bone Defects in Total Knee Arthroplasty Based on Topology Optimization
title_full_unstemmed	Design of Porous Metal Block Augmentation to Treat Tibial Bone Defects in Total Knee Arthroplasty Based on Topology Optimization
title_sort	design of porous metal block augmentation to treat tibial bone defects in total knee arthroplasty based on topology optimization
publisher	Frontiers Media S.A.
publishDate	2021
url	https://doaj.org/article/31b4deb9f35e46dca3a4ffef70fefc93
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Design of Porous Metal Block Augmentation to Treat Tibial Bone Defects in Total Knee Arthroplasty Based on Topology Optimization

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