Non-enzymatic pyridine ring formation in the biosynthesis of the rubrolone tropolone alkaloids

The biosynthesis of pyridine rings is still poorly understood. Here the authors propose a biosynthetic pathway for pyridine-containing rubrolones, which is characterized by a non-enzymatic condensation and cyclization of the pyridine moiety.

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Autores principales: Yijun Yan, Jing Yang, Zhiyin Yu, Mingming Yu, Ya-Tuan Ma, Li Wang, Can Su, Jianying Luo, Geoffrey P. Horsman, Sheng-Xiong Huang
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Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/31b58558e98149e0865282c772e6c8b2
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spelling oai:doaj.org-article:31b58558e98149e0865282c772e6c8b22021-12-02T15:35:46ZNon-enzymatic pyridine ring formation in the biosynthesis of the rubrolone tropolone alkaloids10.1038/ncomms130832041-1723https://doaj.org/article/31b58558e98149e0865282c772e6c8b22016-10-01T00:00:00Zhttps://doi.org/10.1038/ncomms13083https://doaj.org/toc/2041-1723The biosynthesis of pyridine rings is still poorly understood. Here the authors propose a biosynthetic pathway for pyridine-containing rubrolones, which is characterized by a non-enzymatic condensation and cyclization of the pyridine moiety.Yijun YanJing YangZhiyin YuMingming YuYa-Tuan MaLi WangCan SuJianying LuoGeoffrey P. HorsmanSheng-Xiong HuangNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Yijun Yan
Jing Yang
Zhiyin Yu
Mingming Yu
Ya-Tuan Ma
Li Wang
Can Su
Jianying Luo
Geoffrey P. Horsman
Sheng-Xiong Huang
Non-enzymatic pyridine ring formation in the biosynthesis of the rubrolone tropolone alkaloids
description The biosynthesis of pyridine rings is still poorly understood. Here the authors propose a biosynthetic pathway for pyridine-containing rubrolones, which is characterized by a non-enzymatic condensation and cyclization of the pyridine moiety.
format article
author Yijun Yan
Jing Yang
Zhiyin Yu
Mingming Yu
Ya-Tuan Ma
Li Wang
Can Su
Jianying Luo
Geoffrey P. Horsman
Sheng-Xiong Huang
author_facet Yijun Yan
Jing Yang
Zhiyin Yu
Mingming Yu
Ya-Tuan Ma
Li Wang
Can Su
Jianying Luo
Geoffrey P. Horsman
Sheng-Xiong Huang
author_sort Yijun Yan
title Non-enzymatic pyridine ring formation in the biosynthesis of the rubrolone tropolone alkaloids
title_short Non-enzymatic pyridine ring formation in the biosynthesis of the rubrolone tropolone alkaloids
title_full Non-enzymatic pyridine ring formation in the biosynthesis of the rubrolone tropolone alkaloids
title_fullStr Non-enzymatic pyridine ring formation in the biosynthesis of the rubrolone tropolone alkaloids
title_full_unstemmed Non-enzymatic pyridine ring formation in the biosynthesis of the rubrolone tropolone alkaloids
title_sort non-enzymatic pyridine ring formation in the biosynthesis of the rubrolone tropolone alkaloids
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/31b58558e98149e0865282c772e6c8b2
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AT cansu nonenzymaticpyridineringformationinthebiosynthesisoftherubrolonetropolonealkaloids
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