Non-enzymatic pyridine ring formation in the biosynthesis of the rubrolone tropolone alkaloids

The biosynthesis of pyridine rings is still poorly understood. Here the authors propose a biosynthetic pathway for pyridine-containing rubrolones, which is characterized by a non-enzymatic condensation and cyclization of the pyridine moiety.

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Bibliographic Details
Main Authors: Yijun Yan, Jing Yang, Zhiyin Yu, Mingming Yu, Ya-Tuan Ma, Li Wang, Can Su, Jianying Luo, Geoffrey P. Horsman, Sheng-Xiong Huang
Format: article
Language:EN
Published: Nature Portfolio 2016
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Online Access:https://doaj.org/article/31b58558e98149e0865282c772e6c8b2
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